Gene name: ATP6V1C2

Uniprot entry:

Q8NEY4

Protein names:

V-type proton ATPase subunit C 2 (V-ATPase subunit C 2) (Vacuolar proton pump subunit C 2)

Protein sequence:

1_MSEFW 6_ LISAP 11_ GDKEN 16_ LQALE 21_ RMNTV 26_ TSKSN 31_ LSYNT 36_ KFAIP 41_ DFKVG 46_ TLDSL 51_ VGLSD 56_ ELGKL 61_ DTFAE 66_ SLIRR 71_ MAQSV 76_ VEVME 81_ DSKGK 86_ VQEHL 91_ LANGV 96_ DLTSF 101_ VTHFE 106_ WDMAK 111_ YPVKQ 116_ PLVSV 121_ VDTIA 126_ KQLAQ 131_ IEMDL 136_ KSRTA 141_ AYNTL 146_ KTNLE 151_ NLEKK 156_ SMGNL 161_ FTRTL 166_ SDIVS 171_ KEDFV 176_ LDSEY 181_ LVTLL 186_ VIVPK 191_ PNYSQ 196_ WQKTY 201_ ESLSD 206_ MVVPR 211_ STKLI 216_ TEDKE 221_ GGLFT 226_ VTLFR 231_ KVIED 236_ FKTKA 241_ KENKF 246_ TVREF 251_ YYDEK 256_ EIERE 261_ REEMA 266_ RLLSD 271_ KKQQY 276_ QTSCV 281_ ALKKG 286_ SSTFP 291_ DHKVK 296_ VTPLG 301_ NPDRP 306_ AAGQT 311_ DRERE 316_ SEGEG 321_ EGPLL 326_ RWLKV 331_ NFSEA 336_ FIAWI 341_ HIKAL 346_ RVFVE 351_ SVLRY 356_ GLPVN 361_ FQAVL 366_ LQPHK 371_ KSSTK 376_ RLREV 381_ LNSVF 386_ RHLDE 391_ VAATS 396_ ILDAS 401_ VEIPG 406_ LQLNN 411_ QDYFP 416_ YVYFH 421_IDLSL

Protein annotations

Protein functions:

1: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity (By similarity)