Gene name: AKR7L

Uniprot entry:

Q8NHP1

Protein names:

Aflatoxin B1 aldehyde reductase member 4 (EC 1.-.-.-) (AFB1 aldehyde reductase 3) (AFB1-AR 3) (Aldoketoreductase 7-like)

Protein sequence:

1_MSRQL 6_ SRARP 11_ ATVLG 16_ AMEMG 21_ RRMDA 26_ PTSAA 31_ VTRAF 36_ LERGH 41_ TEIDT 46_ AFLYS 51_ DGQSE 56_ TILGG 61_ LGLRM 66_ GSSDC 71_ RVKIA 76_ TKANP 81_ WIGNS 86_ LKPDS 91_ VRSQL 96_ ETSLK 101_ RLQCP 106_ RVDLF 111_ YLHAP 116_ DHSAP 121_ VEETL 126_ RACHQ 131_ LHQEG 136_ KFVEL 141_ GLSNY 146_ AAWEV 151_ AEICT 156_ LCKSN 161_ GWILP 166_ TVYQG 171_ MYSAT 176_ TRQVE 181_ TELFP 186_ CLRHF 191_ GLRFY 196_ AYNPL 201_ AGGLL 206_ TGKYK 211_ YEDKD 216_ GKQPV 221_ GRFFG 226_ TQWAE 231_ IYRNH 236_ FWKEH 241_ HFEGI 246_ ALVEK 251_ ALQAA 256_ YGASA 261_ PSMTS 266_ AALRW 271_ MYHHS 276_ QLQGA 281_ HGDAV 286_ ILGMS 291_ SLEQL 296_ EQNLA 301_ AAEEG 306_ PLEPA 311_ VVDAF 316_ NQAWH 321_ LFAHE 326_CPNYF

Protein annotations

Protein functions:

1: Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen (By similarity)