Telomere repeats-binding bouquet formation protein 2
1_MFQGQ 6_ RGWFC 11_ GSVSQ 16_ DLRQF 21_ WVAEG 26_ GTISD 31_ PRAAD 36_ FLFSC 41_ DASHP 46_ DTLRI 51_ YQSLD 56_ YIEDN 61_ ATVFH 66_ AYYLS 71_ AVANA 76_ KIKNS 81_ VALGH 86_ FILPP 91_ ACLQK 96_ EIRRK 101_ IGSFI 106_ WEQDQ 111_ HFLIE 116_ KHDEV 121_ TPNEI 126_ KTLRE 131_ NSELA 136_ TEHKK 141_ ELSKS 146_ PEKHF 151_ IRTPV 156_ VEKQM 161_ YFPLQ 166_ NYPVN 171_ NMVTG 176_ YISID 181_ AMKKF 186_ LGELH 191_ DFIPG 196_ TSGYL 201_ AYHVQ 206_ NEINM 211_SAIKN
1: Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes: in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and promotes release of the shelterin/telosome complex from telomeric DNA