Secretory carrier-associated membrane protein 5 (Secretory carrier membrane protein 5) (hSCAMP5)
1_MAEKV 6_ NNFPP 11_ LPKFI 16_ PLKPC 21_ FYQDF 26_ EADIP 31_ PQHVS 36_ MTKRL 41_ YYLWM 46_ LNSVT 51_ LAVNL 56_ VGCLA 61_ WLIGG 66_ GGATN 71_ FGLAF 76_ LWLIL 81_ FTPCS 86_ YVCWF 91_ RPIYK 96_ AFKTD 101_ SSFSF 106_ MAFFF 111_ TFMAQ 116_ LVISI 121_ IQAVG 126_ IPGWG 131_ VCGWI 136_ ATISF 141_ FGTNI 146_ GSAVV 151_ MLIPT 156_ VMFTV 161_ MAVFS 166_ FIALS 171_ MVHKF 176_ YRGSG 181_ GSFSK 186_ AQEEW 191_ TTGAW 196_ KNPHV 201_ QQAAQ 206_ NAAMG 211_ AAQGA 216_ MNQPQ 221_ TQYSA 226_TPNYT
1: Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT) in case of endoplasmic reticulum stress by inhibiting the endocytosis pathway