Growth arrest and DNA damage-inducible proteins-interacting protein 1 (39S ribosomal protein L59, mitochondrial) (MRP-L59) (CKII beta-associating protein) (CR6-interacting factor 1) (CRIF1) (Mitochondrial large ribosomal subunit protein mL64) (Papillomavirus L2-interacting nuclear protein 1) (PLINP) (PLINP-1) (p53-responsive gene 6 protein)
1_MAASV 6_ RQARS 11_ LLGVA 16_ ATLAP 21_ GSRGY 26_ RARPP 31_ PRRRP 36_ GPRWP 41_ DPEDL 46_ LTPRW 51_ QLGPR 56_ YAAKQ 61_ FARYG 66_ AASGV 71_ VPGSL 76_ WPSPE 81_ QLREL 86_ EAEER 91_ EWYPS 96_ LATMQ 101_ ESLRV 106_ KQLAE 111_ EQKRR 116_ EREQH 121_ IAECM 126_ AKMPQ 131_ MIVNW 136_ QQQQR 141_ ENWEK 146_ AQADK 151_ ERRAR 156_ LQAEA 161_ QELLG 166_ YQVDP 171_ RSARF 176_ QELLQ 181_ DLEKK 186_ ERKRL 191_ KEEKQ 196_ KRKKE 201_ ARAAA 206_ LAAAV 211_ AQDPA 216_ASGAP
1: Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but also occur in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis