SUN domain-containing protein 3 (Sad1/unc-84 domain-containing protein 1)
1_MSGKT 6_ KARRA 11_ AMFFR 16_ RCSED 21_ ASGSA 26_ SGNAL 31_ LSEDE 36_ NPDAN 41_ GVTRS 46_ WKIIL 51_ STMLT 56_ LTFLL 61_ VGLLN 66_ HQWLK 71_ ETDVP 76_ QKSRQ 81_ LYAII 86_ AEYGS 91_ RLYKY 96_ QARLR 101_ MPKEQ 106_ LELLK 111_ KESQN 116_ LENNF 121_ RQILF 126_ LIEQI 131_ DVLKA 136_ LLRDM 141_ KDGMD 146_ NNHNW 151_ NTHGD 156_ PVEDP 161_ DHTEE 166_ VSNLV 171_ NYVLK 176_ KLRED 181_ QVEMA 186_ DYALK 191_ SAGAS 196_ IIEAG 201_ TSESY 206_ KNNKA 211_ KLYWH 216_ GIGFL 221_ NHEMP 226_ PDIIL 231_ QPDVY 236_ PGKCW 241_ AFPGS 246_ QGHTL 251_ IKLAT 256_ KIIPT 261_ AVTME 266_ HISEK 271_ VSPSG 276_ NISSA 281_ PKEFS 286_ VYGIT 291_ KKCEG 296_ EEIFL 301_ GQFIY 306_ NKTGT 311_ TVQTF 316_ ELQHA 321_ VSEYL 326_ LCVKL 331_ NIFSN 336_ WGHPK 341_ YTCLY 346_ RFRVH 351_GTPGK
1: As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nuclear remodeling during sperm head formation in spermatogenesis. A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette