Protein NDNF (Neuron-derived neurotrophic factor)
1_MVLLH 6_ WCLLW 11_ LLFPL 16_ SSRTQ 21_ KLPTR 26_ DEELF 31_ QMQIR 36_ DKAFF 41_ HDSSV 46_ IPDGA 51_ EISSY 56_ LFRDT 61_ PKRYF 66_ FVVEE 71_ DNTPL 76_ SVTVT 81_ PCDAP 86_ LEWKL 91_ SLQEL 96_ PEDRS 101_ GEGSG 106_ DLEPL 111_ EQQKQ 116_ QIINE 121_ EGTEL 126_ FSYKG 131_ NDVEY 136_ FISSS 141_ SPSGL 146_ YQLDL 151_ LSTEK 156_ DTHFK 161_ VYATT 166_ TPESD 171_ QPYPE 176_ LPYDP 181_ RVDVT 186_ SLGRT 191_ TVTLA 196_ WKPSP 201_ TASLL 206_ KQPIQ 211_ YCVVI 216_ NKEHN 221_ FKSLC 226_ AVEAK 231_ LSADD 236_ AFMMA 241_ PKPGL 246_ DFSPF 251_ DFAHF 256_ GFPSD 261_ NSGKE 266_ RSFQA 271_ KPSPK 276_ LGRHV 281_ YSRPK 286_ VDIQK 291_ ICIGN 296_ KNIFT 301_ VSDLK 306_ PDTQY 311_ YFDVF 316_ VVNIN 321_ SNMST 326_ AYVGT 331_ FARTK 336_ EEAKQ 341_ KTVEL 346_ KDGKI 351_ TDVFV 356_ KRKGA 361_ KFLRF 366_ APVSS 371_ HQKVT 376_ FFIHS 381_ CLDAV 386_ QIQVR 391_ RDGKL 396_ LLSQN 401_ VEGIQ 406_ QFQLR 411_ GKPKA 416_ KYLVR 421_ LKGNK 426_ KGASM 431_ LKILA 436_ TTRPT 441_ KQSFP 446_ SLPED 451_ TRIKA 456_ FDKLR 461_ TCSSA 466_ TVAWL 471_ GTQER 476_ NKFCI 481_ YKKEV 486_ DDNYN 491_ EDQKK 496_ REQNQ 501_ CLGPD 506_ IRKKS 511_ EKVLC 516_ KYFHS 521_ QNLQK 526_ AVTTE 531_ TIKGL 536_ QPGKS 541_ YLLDV 546_ YVIGH 551_ GGHSV 556_ KYQSK 561_VVKTR
1: Secretory protein that plays a role in various cellular processes (PubMed:20969804, PubMed:24706764, PubMed:31883645). Acts as a chemorepellent acting on gonadotropin-releasing hormone (GnRH) expressing neurons regulating their migration to the hypothalamus (PubMed:31883645). Also promotes neuron migration, growth and survival as well as neurite outgrowth and is involved in the development of the olfactory system (PubMed:20969804, PubMed:31883645). May also act through the regulation of growth factors activity and downstream signaling (PubMed:31883645). Also regulates extracellular matrix assembly and cell adhesiveness (By similarity). Promotes endothelial cell survival, vessel formation and plays an important role in the process of revascularization through NOS3-dependent mechanisms (PubMed:24706764)