Phosphatidylinositol-glycan biosynthesis class X protein (PIG-X)
1_MAARV 6_ AAVRA 11_ AAWLL 16_ LGAAT 21_ GLTRG 26_ PAAAF 31_ TAARS 36_ DAGIR 41_ AMCSE 46_ IILRQ 51_ EVLKD 56_ GFHRD 61_ LLIKV 66_ KFGES 71_ IEDLH 76_ TCRLL 81_ IKQDI 86_ PAGLY 91_ VDPYE 96_ LASLR 101_ ERNIT 106_ EAVMV 111_ SENFD 116_ IEAPN 121_ YLSKE 126_ SEVLI 131_ YARRD 136_ SQCID 141_ CFQAF 146_ LPVHC 151_ RYHRP 156_ HSEDG 161_ EASIV 166_ VNNPD 171_ LLMFC 176_ DQEFP 181_ ILKCW 186_ AHSEV 191_ AAPCA 196_ LENED 201_ ICQWN 206_ KMKYK 211_ SVYKN 216_ VILQV 221_ PVGLT 226_ VHTSL 231_ VCSVT 236_ LLITI 241_ LCSTL 246_ ILVAV 251_FKYGH
1: Stabilizing subunit of the glycosylphosphatidylinositol-mannosyltransferase I complex which catalyzes the transfer of the first mannose, via an alpha-1,4 bond from a dolichol-phosphate-mannose (Dol-P-Man) to the glucosaminyl acyl phosphatidylinositol (GlcN-(acyl)PI) intermediate to generate alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol and participates in the sixth step of the glycosylphosphatidylinositol-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM