WD repeat-containing protein 20 (Protein DMR)
1_MATEG 6_ GGKEM 11_ NEIKT 16_ QFTTR 21_ EGLYK 26_ LLPHS 31_ EYSRP 36_ NRVPF 41_ NSQGS 46_ NPVRV 51_ SFVNL 56_ NDQSG 61_ NGDRL 66_ CFNVG 71_ RELYF 76_ YIYKG 81_ VRKAA 86_ DLSKP 91_ IDKRI 96_ YKGTQ 101_ PTCHD 106_ FNHLT 111_ ATAES 116_ VSLLV 121_ GFSAG 126_ QVQLI 131_ DPIKK 136_ ETSKL 141_ FNEER 146_ LIDKS 151_ RVTCV 156_ KWVPG 161_ SESLF 166_ LVAHS 171_ SGNMY 176_ LYNVE 181_ HTCGT 186_ TAPHY 191_ QLLKQ 196_ GESFA 201_ VHTCK 206_ SKSTR 211_ NPLLK 216_ WTVGE 221_ GALNE 226_ FAFSP 231_ DGKFL 236_ ACVSQ 241_ DGFLR 246_ VFNFD 251_ SVELH 256_ GTMKS 261_ YFGGL 266_ LCVCW 271_ SPDGK 276_ YIVTG 281_ GEDDL 286_ VTVWS 291_ FVDCR 296_ VIARG 301_ HGHKS 306_ WVSVV 311_ AFDPY 316_ TTSVE 321_ EGDPM 326_ EFSGS 331_ DEDFQ 336_ DLLHF 341_ GRDRA 346_ NSTQS 351_ RLSKR 356_ NSTDS 361_ RPVSV 366_ TYRFG 371_ SVGQD 376_ TQLCL 381_ WDLTE 386_ DILFP 391_ HQPLS 396_ RARTH 401_ TNVMN 406_ ATSPP 411_ AGSNG 416_ NSVTT 421_ PGNSV 426_ PPPLP 431_ RSNSL 436_ PHSAV 441_ SNAGS 446_ KSSVM 451_ DGAIA 456_ SGVSK 461_ FATLS 466_ LHDRK 471_ ERHHE 476_ KDHKR 481_ NHSMG 486_ HISSK 491_ SSDKL 496_ NLVTK 501_ TKTDP 506_ AKTLG 511_ TPLCP 516_ RMEDV 521_ PLLEP 526_ LICKK 531_ IAHER 536_ LTVLI 541_ FLEDC 546_ IVTAC 551_ QEGFI 556_ CTWGR 561_PGKVV
1: Regulator of deubiquitinating complexes. Activates deubiquitinating activity of complexes containing USP12 (PubMed:20147737, PubMed:27373336). Anchors at the base of the ubiquitin-contacting loop of USP12 and remotely modulates the catalytic center of the enzyme (PubMed:27373336). Regulates shuttling of the USP12 deubiquitinase complex between the plasma membrane, cytoplasm and nucleus (PubMed:30466959)