Gene name: TRMT10A

Uniprot entry:

Q8TBZ6

Protein names:

tRNA methyltransferase 10 homolog A (EC 2.1.1.221) (RNA (guanine-9-)-methyltransferase domain-containing protein 2) (tRNA (guanine(9)-N(1))-methyltransferase TRMT10A)

Protein sequence:

1_MSSEM 6_ LPAFI 11_ ETSNV 16_ DKKQG 21_ INEDQ 26_ EESQK 31_ PRLGE 36_ GCEPI 41_ SKRQM 46_ KKLIK 51_ QKQWE 56_ EQREL 61_ RKQKR 66_ KEKRK 71_ RKKLE 76_ RQCQM 81_ EPNSD 86_ GHDRK 91_ RVRRD 96_ VVHST 101_ LRLII 106_ DCSFD 111_ HLMVL 116_ KDIKK 121_ LHKQI 126_ QRCYA 131_ ENRRA 136_ LHPVQ 141_ FYLTS 146_ HGGQL 151_ KKNMD 156_ ENDKG 161_ WVNWK 166_ DIHIK 171_ PEHYS 176_ ELIKK 181_ EDLIY 186_ LTSDS 191_ PNILK 196_ ELDES 201_ KAYVI 206_ GGLVD 211_ HNHHK 216_ GLTYK 221_ QASDY 226_ GINHA 231_ QLPLG 236_ NFVKM 241_ NSRKV 246_ LAVNH 251_ VFEII 256_ LEYLE 261_ TRDWQ 266_ EAFFT 271_ ILPQR 276_ KGAVP 281_ TDKAC 286_ ESASH 291_ DNQSV 296_ RMEEG 301_ GSDSD 306_ SSEEE 311_ YSRNE 316_ LDSPH 321_ EEKQD 326_ KENHT 331_ESTVN

Protein annotations

Protein functions:

1: S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in tRNAs (PubMed:23042678, PubMed:25053765). Probably not able to catalyze formation of N(1)-methyladenine at position 9 (m1A9) in tRNAs (PubMed:23042678)