POC1 centriolar protein homolog B (Pix1) (Proteome of centriole protein 1B) (WD repeat-containing protein 51B)
1_MASAT 6_ EDPVL 11_ ERYFK 16_ GHKAA 21_ ITSLD 26_ LSPNG 31_ KQLAT 36_ ASWDT 41_ FLMLW 46_ NFKPH 51_ ARAYR 56_ YVGHK 61_ DVVTS 66_ VQFSP 71_ HGNLL 76_ ASASR 81_ DRTVR 86_ LWIPD 91_ KRGKF 96_ SEFKA 101_ HTAPV 106_ RSVDF 111_ SADGQ 116_ FLATA 121_ SEDKS 126_ IKVWS 131_ MYRQR 136_ FLYSL 141_ YRHTH 146_ WVRCA 151_ KFSPD 156_ GRLIV 161_ SCSED 166_ KTIKI 171_ WDTTN 176_ KQCVN 181_ NFSDS 186_ VGFAN 191_ FVDFN 196_ PSGTC 201_ IASAG 206_ SDQTV 211_ KVWDV 216_ RVNKL 221_ LQHYQ 226_ VHSGG 231_ VNCIS 236_ FHPSG 241_ NYLIT 246_ ASSDG 251_ TLKIL 256_ DLLEG 261_ RLIYT 266_ LQGHT 271_ GPVFT 276_ VSFSK 281_ GGELF 286_ ASGGA 291_ DTQVL 296_ LWRTN 301_ FDELH 306_ CKGLT 311_ KRNLK 316_ RLHFD 321_ SPPHL 326_ LDIYP 331_ RTPHP 336_ HEEKV 341_ ETVEI 346_ NPKLE 351_ VIDLQ 356_ ISTPP 361_ VMDIL 366_ SFDST 371_ TTTET 376_ SGRTL 381_ PDKGE 386_ EACGY 391_ FLNPS 396_ LMSPE 401_ CLPTT 406_ TKKKT 411_ EDMSD 416_ LPCES 421_ QRSIP 426_ LAVTD 431_ ALEHI 436_ MEQLN 441_ VLTQT 446_ VSILE 451_ QRLTL 456_ TEDKL 461_ KDCLE 466_ NQQKL 471_FSAVQ
1: Plays an important role in centriole assembly and/or stability and ciliogenesis (PubMed:20008567, PubMed:32060285). Involved in early steps of centriole duplication, as well as in the later steps of centriole length control (PubMed:19109428). Acts in concert with POC1A to ensure centriole integrity and proper mitotic spindle formation (PubMed:32060285). Required for primary cilia formation, ciliary length and also cell proliferation (PubMed:23015594). Required for retinal integrity (PubMed:25044745). Acts as a positive regulator of centriole elongation (PubMed:37934472)