Coiled-coil domain-containing glutamate-rich protein 1
1_MTQTL 6_ DTRED 11_ PLNLG 16_ GGGGG 21_ GCGCG 26_ WAHSA 31_ SLSSW 36_ SSCHR 41_ RRPGA 46_ PAYNR 51_ PHRYS 56_ PKTEY 61_ GPPRK 66_ QPKQQ 71_ HGPGF 76_ WFQPP 81_ VCSNW 86_ GCWGG 91_ PWRPP 96_ PPGFW 101_ KFPCP 106_ VQVFR 111_ VYGLH 116_ PLCFC 121_ CCSCW 126_ SGSWN 131_ PGWVK 136_ PPGRK 141_ KRWGR 146_ RGRGL 151_ RHHPR 156_ HSYPR 161_ SPPAD 166_ VSTLP 171_ RPVKL 176_ YEWRE 181_ PGMRA 186_ PPNTT 191_ QFIMN 196_ QIYED 201_ MRQQE 206_ KVERQ 211_ QEALR 216_ AQKAT 221_ VSGEA 226_ SPARS 231_ SGNDA 236_ PPGGS 241_ KETWG 246_ LQETL 251_ YGFVQ 256_ NPSLA 261_ FSPNP 266_ EENQS 271_ LAPLL 276_ VEEEE 281_ EKKND 286_ DEEEY 291_ DQEVC 296_ DAKEA 301_ SEEEE 306_ EVEDE 311_ EEEVE 316_ DEEEE 321_ EVEEA 326_ EYVEE 331_ GEEEL 336_ EEEEL 341_ EEEEE 346_ VLEEN 351_ EQRGE 356_ EFHLP 361_ LEMPL 366_ SIFVE 371_ AEEKR 376_ ENFIS 381_ CTFLN 386_ PEQII 391_ PKVPQ 396_ ESLFM 401_AQDFN
1: Regulator of histone epigenetic modifications and chromatin compaction into the sperm head, required for histone-to-protamine (HTP) transition. HTP is a key event in which somatic histones are first replaced by testis-specific histone variants, then transition proteins (TNPs) are incorporated into the spermatid nucleus, and finally protamines (PRMs) replace the TNPs to promote chromatin condensation