Gene name: MRAP

Uniprot entry:

Q8TCY5

Protein names:

Melanocortin-2 receptor accessory protein (B27) (Fat cell-specific low molecular weight protein) (Fat tissue-specific low MW protein)

Protein sequence:

1_MANGT 6_ NASAP 11_ YYSYE 16_ YYLDY 21_ LDLIP 26_ VDEKK 31_ LKAHK 36_ HSIVI 41_ AFWVS 46_ LAAFV 51_ VLLFL 56_ ILLYM 61_ SWSAS 66_ PQMRN 71_ SPKHH 76_ QTCPW 81_ SHGLN 86_ LHLCI 91_ QKCLP 96_ CHREP 101_ LATSQ 106_ AQASS 111_ VEPGS 116_ RTGPD 121_ QPLRQ 126_ ESSST 131_ LPLGG 136_ FQTHP 141_ TLLWE 146_ LTLNG 151_ GPLVR 156_ SKPSE 161_ PPPGD 166_RTSQL

Protein annotations

Protein functions:

1: Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells