Potassium voltage-gated channel subfamily G member 4 (Voltage-gated potassium channel subunit Kv6.4)
1_MPMPS 6_ RDGGL 11_ HPRHH 16_ HYGSH 21_ SPWSQ 26_ LLSSP 31_ METPS 36_ IKGLY 41_ YRRVR 46_ KVGAL 51_ DASPV 56_ DLKKE 61_ ILINV 66_ GGRRY 71_ LLPWS 76_ TLDRF 81_ PLSRL 86_ SKLRL 91_ CRSYE 96_ EIVQL 101_ CDDYD 106_ EDSQE 111_ FFFDR 116_ SPSAF 121_ GVIVS 126_ FLAAG 131_ KLVLL 136_ QEMCA 141_ LSFQE 146_ ELAYW 151_ GIEEA 156_ HLERC 161_ CLRKL 166_ LRKLE 171_ ELEEL 176_ AKLHR 181_ EDVLR 186_ QQRET 191_ RRPAS 196_ HSSRW 201_ GLCMN 206_ RLREM 211_ VENPQ 216_ SGLPG 221_ KVFAC 226_ LSILF 231_ VATTA 236_ VSLCV 241_ STMPD 246_ LRAEE 251_ DQGEC 256_ SRKCY 261_ YIFIV 266_ ETICV 271_ AWFSL 276_ EFCLR 281_ FVQAQ 286_ DKCQF 291_ FQGPL 296_ NIIDI 301_ LAISP 306_ YYVSL 311_ AVSEE 316_ PPEDG 321_ ERPSG 326_ SSYLE 331_ KVGLV 336_ LRVLR 341_ ALRIL 346_ YVMRL 351_ ARHSL 356_ GLQTL 361_ GLTVR 366_ RCTRE 371_ FGLLL 376_ LFLAV 381_ AITLF 386_ SPLVY 391_ VAEKE 396_ SGRVL 401_ EFTSI 406_ PASYW 411_ WAIIS 416_ MTTVG 421_ YGDMV 426_ PRSVP 431_ GQMVA 436_ LSSIL 441_ SGILI 446_ MAFPA 451_ TSIFH 456_ TFSHS 461_ YLELK 466_ KEQEQ 471_ LQARL 476_ RHLQN 481_ TGPAS 486_ ECELL 491_ DPHVA 496_ SEHEL 501_ MNDVN 506_ DLILE 511_GPALP
1: Regulatory subunit of the voltage-gated potassium (Kv) channel which, when coassembled with KCNB1, modulates the kinetics parameters of the heterotetrameric channel namely the time course of activation, deactivation and inactivation and on the voltage-dependence of activation (PubMed:12060745, PubMed:19074135). Potassium channel subunit that does not form functional channels by itself (Probable) (PubMed:12060745). Reduces the deactivation rate (PubMed:12060745, PubMed:19074135). Modulates the threshold for activation by shifting by approximately 20 mV in hyperpolarizing direction (PubMed:12060745). Markedly changes the inactivation by shifting the voltage dependence of inactivation by approximately 40 mV in hyperpolarizing direction (PubMed:12060745). Acceleratee activation and enhances the time course of activation (PubMed:12060745)