Gene name: RNASEH2C

Uniprot entry:

Q8TDP1

Protein names:

Ribonuclease H2 subunit C (RNase H2 subunit C) (Aicardi-Goutieres syndrome 3 protein) (AGS3) (RNase H1 small subunit) (Ribonuclease HI subunit C)

Protein sequence:

1_MESGD 6_ EAAIE 11_ RHRVH 16_ LRSAT 21_ LRDAV 26_ PATLH 31_ LLPCE 36_ VAVDG 41_ PAPVG 46_ RFFTP 51_ AIRQG 56_ PEGLE 61_ VSFRG 66_ RCLRG 71_ EEVAV 76_ PPGLV 81_ GYVMV 86_ TEEKK 91_ VSMGK 96_ PDPLR 101_ DSGTD 106_ DQEEE 111_ PLERD 116_ FDRFI 121_ GATAN 126_ FSRFT 131_ LWGLE 136_ TIPGP 141_ DAKVR 146_ GALTW 151_ PSLAA 156_AIHAQ

Protein annotations

Protein functions:

1: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes