TRAF3-interacting protein 1 (Interleukin-13 receptor alpha 1-binding protein 1) (Intraflagellar transport protein 54 homolog) (Microtubule-interacting protein associated with TRAF3) (MIP-T3)
1_MNAAV 6_ VRRTQ 11_ EALGK 16_ VIRRP 21_ PLTEK 26_ LLSKP 31_ PFRYL 36_ HDIIT 41_ EVIRM 46_ TGFMK 51_ GLYTD 56_ AEMKS 61_ DNVKD 66_ KDAKI 71_ SFLQK 76_ AIDVV 81_ VMVSG 86_ EPLLA 91_ KPARI 96_ VAGHE 101_ PERTN 106_ ELLQI 111_ IGKCC 116_ LNKLS 121_ SDDAV 126_ RRVLA 131_ GEKGE 136_ VKGRA 141_ SLTSR 146_ SQELD 151_ NKNVR 156_ EEESR 161_ VHKNT 166_ EDRGD 171_ AEIKE 176_ RSTSR 181_ DRKQK 186_ EELKE 191_ DRKPR 196_ EKDKD 201_ KEKAK 206_ ENGGN 211_ RHREG 216_ ERERA 221_ KARAR 226_ PDNER 231_ QKDRG 236_ NRERD 241_ RDSER 246_ KKETE 251_ RKSEG 256_ GKEKE 261_ RLRDR 266_ DRERD 271_ RDKGK 276_ DRDRR 281_ RVKNG 286_ EHSWD 291_ LDREK 296_ NREHD 301_ KPEKK 306_ SASSG 311_ EMSKK 316_ LSDGT 321_ FKDSK 326_ AETET 331_ EISTR 336_ ASKSL 341_ TTKTS 346_ KRRSK 351_ NSVEG 356_ RKEDN 361_ ISAKS 366_ LDSIV 371_ SGINN 376_ EPNQE 381_ TTTSE 386_ IGTKE 391_ ANINS 396_ TSISD 401_ DNSAS 406_ LRCEN 411_ IQPNP 416_ TEKQK 421_ GDSTS 426_ DAEGD 431_ AGPAG 436_ QDKSE 441_ VPETP 446_ EIPNE 451_ LSSNI 456_ RRIPR 461_ PGSAR 466_ PAPPR 471_ VKRQD 476_ SMEAL 481_ QMDRS 486_ GSGKT 491_ VSNVI 496_ TESHN 501_ SDNEE 506_ DDQFV 511_ VEAAP 516_ QLSEM 521_ SEIEM 526_ VTAVE 531_ LEEEE 536_ KHGGL 541_ VKKIL 546_ ETKKD 551_ YEKLQ 556_ QSPKP 561_ GEKER 566_ SLFES 571_ AWKKE 576_ KDIVS 581_ KEIEK 586_ LRTSI 591_ QTLCK 596_ SALPL 601_ GKIMD 606_ YIQED 611_ VDAMQ 616_ NELQM 621_ WHSEN 626_ RQHAE 631_ ALQQE 636_ QRITD 641_ CAVEP 646_ LKAEL 651_ AELEQ 656_ LIKDQ 661_ QDKIC 666_ AVKAN 671_ ILKNE 676_ EKIQK 681_ MVYSI 686_NLTSR
1: Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Involved in kidney development and epithelial morphogenesis. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels (PubMed:26487268). Involved in ciliogenesis (By similarity)