Elongator complex protein 5 (Dermal papilla-derived protein 6) (S-phase 2 protein)
1_MTPSE 6_ GARAG 11_ TGREL 16_ EMLDS 21_ LLALG 26_ GLVLL 31_ RDSVE 36_ WEGRS 41_ LLKAL 46_ VKKSA 51_ LCGEQ 56_ VHILG 61_ CEVSE 66_ EEFRE 71_ GFDSD 76_ INNRL 81_ VYHDF 86_ FRDPL 91_ NWSKT 96_ EEAFP 101_ GGPLG 106_ ALRAM 111_ CKRTD 116_ PVPVT 121_ IALDS 126_ LSWLL 131_ LRLPC 136_ TTLCQ 141_ VLHAV 146_ SHQDS 151_ CPGDS 156_ SSVGK 161_ VSVLG 166_ LLHEE 171_ LHGPG 176_ PVGAL 181_ SSLAQ 186_ TEVTL 191_ GGTMG 196_ QASAH 201_ ILCRR 206_ PRQRP 211_ TDQTQ 216_ WFSIL 221_ PDFSL 226_ DLQEG 231_ PSVES 236_ QPYSD 241_ PHIPP 246_ VDPTT 251_ HLTFN 256_ LHLSK 261_ KEREA 266_ RDSLI 271_ LPFQF 276_ SSEKQ 281_ QALLR 286_ PRPGQ 291_ ATSHI 296_ FYEPD 301_ AYDDL 306_ DQEDP 311_DDDLD
1: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (PubMed:29332244). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (PubMed:29332244). Involved in cell migration (By similarity)