Anion exchange transporter (Solute carrier family 26 member 7)
1_MTGAK 6_ RKKKS 11_ MLWSK 16_ MHTPQ 21_ CEDII 26_ QWCRR 31_ RLPIL 36_ DWAPH 41_ YNLKE 46_ NLLPD 51_ TVSGI 56_ MLAVQ 61_ QVTQG 66_ LAFAV 71_ LSSVH 76_ PVFGL 81_ YGSLF 86_ PAIIY 91_ AIFGM 96_ GHHVA 101_ TGTFA 106_ LTSLI 111_ SANAV 116_ ERIVP 121_ QNMQN 126_ LTTQS 131_ NTSVL 136_ GLSDF 141_ EMQRI 146_ HVAAA 151_ VSFLG 156_ GVIQV 161_ AMFVL 166_ QLGSA 171_ TFVVT 176_ EPVIS 181_ AMTTG 186_ AATHV 191_ VTSQV 196_ KYLLG 201_ MKMPY 206_ ISGPL 211_ GFFYI 216_ YAYVF 221_ ENIKS 226_ VRLEA 231_ LLLSL 236_ LSIVV 241_ LVLVK 246_ ELNEQ 251_ FKRKI 256_ KVVLP 261_ VDLVL 266_ IIAAS 271_ FACYC 276_ TNMEN 281_ TYGLE 286_ VVGHI 291_ PQGIP 296_ SPRAP 301_ PMNIL 306_ SAVIT 311_ EAFGV 316_ ALVGY 321_ VASLA 326_ LAQGS 331_ AKKFK 336_ YSIDD 341_ NQEFL 346_ AHGLS 351_ NIVSS 356_ FFFCI 361_ PSAAA 366_ MGRTA 371_ GLYST 376_ GAKTQ 381_ VACLI 386_ SCIFV 391_ LIVIY 396_ AIGPL 401_ LYWLP 406_ MCVLA 411_ SIIVV 416_ GLKGM 421_ LIQFR 426_ DLKKY 431_ WNVDK 436_ IDWGI 441_ WVSTY 446_ VFTIC 451_ FAANV 456_ GLLFG 461_ VVCTI 466_ AIVIG 471_ RFPRA 476_ MTVSI 481_ KNMKE 486_ MEFKV 491_ KTEMD 496_ SETLQ 501_ QVKII 506_ SINNP 511_ LVFLN 516_ AKKFY 521_ TDLMN 526_ MIQKE 531_ NACNQ 536_ PLDDI 541_ SKCEQ 546_ NTLLN 551_ SLSNG 556_ NCNEE 561_ ASQSC 566_ PNEKC 571_ YLILD 576_ CSGFT 581_ FFDYS 586_ GVSML 591_ VEVYM 596_ DCKGR 601_ SVDVL 606_ LAHCT 611_ ASLIK 616_ AMTYY 621_ GNLDS 626_ EKPIF 631_ FESVS 636_ AAISH 641_ IHSNK 646_ NLSKL 651_SDHSE
1: Acts as an anion channel mediating the transport of chloride, sulfate and oxalate ions (PubMed:11834742). Mediates the transport of bromide, iodide, nitrate, gluconate, thiocyanate and bicarbonate ions (By similarity). Its permeability towards bicarbonate is weak and increases when pH is above 7 (By similarity). Mediates thiocyanate transport in retinal pigment epithelium cells (By similarity). Mediates iodide transport in the thyroid gland, playing an important role in the synthesis of thyroid hormones and the maintenance of thyroid function (PubMed:31372509). Although it is an anion channel, according to PubMed:12736153 and PubMed:32119864 it has been shown to exhibit chloride-bicarbonate exchanger activity