U3 small nucleolar RNA-associated protein 15 homolog
1_MAGYK 6_ PVAIQ 11_ TYPIL 16_ GEKIT 21_ QDTLY 26_ WNNYK 31_ TPVQI 36_ KEFGA 41_ VSKVD 46_ FSPQP 51_ PYNYA 56_ VTASS 61_ RIHIY 66_ GRYSQ 71_ EPIKT 76_ FSRFK 81_ DTAYC 86_ ATFRQ 91_ DGRLL 96_ VAGSE 101_ DGGVQ 106_ LFDIS 111_ GRAPL 116_ RQFEG 121_ HTKAV 126_ HTVDF 131_ TADKY 136_ HVVSG 141_ ADDYT 146_ VKLWD 151_ IPNSK 156_ EILTF 161_ KEHSD 166_ YVRCG 171_ CASKL 176_ NPDLF 181_ ITGSY 186_ DHTVK 191_ MFDAR 196_ TSESV 201_ LSVEH 206_ GQPVE 211_ SVLLF 216_ PSGGL 221_ LVSAG 226_ GRYVK 231_ VWDML 236_ KGGQL 241_ LVSLK 246_ NHHKT 251_ VTCLC 256_ LSSSG 261_ QRLLS 266_ GSLDR 271_ KVKVY 276_ STTSY 281_ KVVHS 286_ FDYAA 291_ SILSL 296_ ALAHE 301_ DETIV 306_ VGMTN 311_ GILSV 316_ KHRKS 321_ EAKKE 326_ SLPRR 331_ RRPAY 336_ RTFIK 341_ GKNYM 346_ KQRDD 351_ ILINR 356_ PAKKH 361_ LELYD 366_ RDLKH 371_ FRISK 376_ ALDRV 381_ LDPTC 386_ TIKTP 391_ EITVS 396_ IIKEL 401_ NRRGV 406_ LANAL 411_ AGRDE 416_ KEISH 421_ VLNFL 426_ IRNLS 431_ QPRFA 436_ PVLIN 441_ AAEII 446_ IDIYL 451_ PVIGQ 456_ SPVVD 461_ KKFLL 466_ LQGLV 471_ EKEID 476_ YQREL 481_ LETLG 486_ MMDML 491_ FATMR 496_ RKEGT 501_ SVLEH 506_ TSDGF 511_PENKK
1: Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I (PubMed:17699751). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797)