Histone-lysine N-methyltransferase, H3 lysine-79 specific (EC 2.1.1.360) (DOT1-like protein) (Histone H3-K79 methyltransferase) (H3-K79-HMTase) (Lysine N-methyltransferase 4)
1_MGEKL 6_ ELRLK 11_ SPVGA 16_ EPAVY 21_ PWPLP 26_ VYDKH 31_ HDAAH 36_ EIIET 41_ IRWVC 46_ EEIPD 51_ LKLAM 56_ ENYVL 61_ IDYDT 66_ KSFES 71_ MQRLC 76_ DKYNR 81_ AIDSI 86_ HQLWK 91_ GTTQP 96_ MKLNT 101_ RPSTG 106_ LLRHI 111_ LQQVY 116_ NHSVT 121_ DPEKL 126_ NNYEP 131_ FSPEV 136_ YGETS 141_ FDLVA 146_ QMIDE 151_ IKMTD 156_ DDLFV 161_ DLGSG 166_ VGQVV 171_ LQVAA 176_ ATNCK 181_ HHYGV 186_ EKADI 191_ PAKYA 196_ ETMDR 201_ EFRKW 206_ MKWYG 211_ KKHAE 216_ YTLER 221_ GDFLS 226_ EEWRE 231_ RIANT 236_ SVIFV 241_ NNFAF 246_ GPEVD 251_ HQLKE 256_ RFANM 261_ KEGGR 266_ IVSSK 271_ PFAPL 276_ NFRIN 281_ SRNLS 286_ DIGTI 291_ MRVVE 296_ LSPLK 301_ GSVSW 306_ TGKPV 311_ SYYLH 316_ TIDRT 321_ ILENY 326_ FSSLK 331_ NPKLR 336_ EEQEA 341_ ARRRQ 346_ QRESK 351_ SNAAT 356_ PTKGP 361_ EGKVA 366_ GPADA 371_ PMDSG 376_ AEEEK 381_ AGAAT 386_ VKKPS 391_ PSKAR 396_ KKKLN 401_ KKGRK 406_ MAGRK 411_ RGRPK 416_ KMNTA 421_ NPERK 426_ PKKNQ 431_ TALDA 436_ LHAQT 441_ VSQTA 446_ ASSPQ 451_ DAYRS 456_ PHSPF 461_ YQLPP 466_ SVQRH 471_ SPNPL 476_ LVAPT 481_ PPALQ 486_ KLLES 491_ FKIQY 496_ LQFLA 501_ YTKTP 506_ QYKAS 511_ LQELL 516_ GQEKE 521_ KNAQL 526_ LGAAQ 531_ QLLSH 536_ CQAQK 541_ EEIRR 546_ LFQQK 551_ LDELG 556_ VKALT 561_ YNDLI 566_ QAQKE 571_ ISAHN 576_ QQLRE 581_ QSEQL 586_ EQDNR 591_ ALRGQ 596_ SLQLL 601_ KARCE 606_ ELQLD 611_ WATLS 616_ LEKLL 621_ KEKQA 626_ LKSQI 631_ SEKQR 636_ HCLEL 641_ QISIV 646_ ELEKS 651_ QRQQE 656_ LLQLK 661_ SCVPP 666_ DDALS 671_ LHLRG 676_ KGALG 681_ RELEP 686_ DASRL 691_ HLELD 696_ CTKFS 701_ LPHLS 706_ SMSPE 711_ LSMNG 716_ QAAGY 721_ ELCGV 726_ LSRPS 731_ SKQNT 736_ PQYLA 741_ SPLDQ 746_ EVVPC 751_ TPSHV 756_ GRPRL 761_ EKLSG 766_ LAAPD 771_ YTRLS 776_ PAKIV 781_ LRRHL 786_ SQDHT 791_ VPGRP 796_ AASEL 801_ HSRAE 806_ HTKEN 811_ GLPYQ 816_ SPSVP 821_ GSMKL 826_ SPQDP 831_ RPLSP 836_ GALQL 841_ AGEKS 846_ SEKGL 851_ RERAY 856_ GSSGE 861_ LITSL 866_ PISIP 871_ LSTVQ 876_ PNKLP 881_ VSIPL 886_ ASVVL 891_ PSRAE 896_ RARST 901_ PSPVL 906_ QPRDP 911_ SSTLE 916_ KQIGA 921_ NAHGA 926_ GSRSL 931_ ALAPA 936_ GFSYA 941_ GSVAI 946_ SGALA 951_ GSPAS 956_ LTPGA 961_ EPATL 966_ DESSS 971_ SGSLF 976_ ATVGS 981_ RSSTP 986_ QHPLL 991_ LAQPR 996_ NSLPA 1001_ SPAHQ 1006_ LSSSP 1011_ RLGGA 1016_ AQGPL 1021_ PEASK 1026_ GDLPS 1031_ DSGFS 1036_ DPESE 1041_ AKRRI 1046_ VFTIT 1051_ TGAGS 1056_ AKQSP 1061_ SSKHS 1066_ PLTAS 1071_ ARGDC 1076_ VPSHG 1081_ QDSRR 1086_ RGRRK 1091_ RASAG 1096_ TPSLS 1101_ AGVSP 1106_ KRRAL 1111_ PSVAG 1116_ LFTQP 1121_ SGSPL 1126_ NLNSM 1131_ VSNIN 1136_ QPLEI 1141_ TAISS 1146_ PETSL 1151_ KSSPV 1156_ PYQDH 1161_ DQPPV 1166_ LKKER 1171_ PLSQT 1176_ NGAHY 1181_ SPLTS 1186_ DEEPG 1191_ SEDEP 1196_ SSARI 1201_ ERKIA 1206_ TISLE 1211_ SKSPP 1216_ KTLEN 1221_ GGGLA 1226_ GRKPA 1231_ PAGEP 1236_ VNSSK 1241_ WKSTF 1246_ SPISD 1251_ IGLAK 1256_ SADSP 1261_ LQASS 1266_ ALSQN 1271_ SLFTF 1276_ RPALE 1281_ EPSAD 1286_ AKLAA 1291_ HPRKG 1296_ FPGSL 1301_ SGADG 1306_ LSPGT 1311_ NPANG 1316_ CTFGG 1321_ GLAAD 1326_ LSLHS 1331_ FSDGA 1336_ SLPHK 1341_ GPEAA 1346_ GLSSP 1351_ LSFPS 1356_ QRGKE 1361_ GSDAN 1366_ PFLSK 1371_ RQLDG 1376_ LAGLK 1381_ GEGSR 1386_ GKEAG 1391_ EGGLP 1396_ LCGPT 1401_ DKTPL 1406_ LSGKA 1411_ AKARD 1416_ REVDL 1421_ KNGHN 1426_ LFISA 1431_ AAVPP 1436_ GSLLS 1441_ GPGLA 1446_ PAASS 1451_ AGGAA 1456_ SSAQT 1461_ HRSFL 1466_ GPFPP 1471_ GPQFA 1476_ LGPMS 1481_ LQANL 1486_ GSVAG 1491_ SSVLQ 1496_ SLFSS 1501_ VPAAA 1506_ GLVHV 1511_ SSAAT 1516_ RLTNS 1521_ HAMGS 1526_ FSGVA 1531_GGTVG
1: Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones (PubMed:12123582). Binds to DNA (PubMed:12628190)