Monocarboxylate transporter 10 (MCT 10) (Aromatic amino acid transporter 1) (Solute carrier family 16 member 10) (T-type amino acid transporter 1)
1_MVLSQ 6_ EEPDS 11_ ARGTS 16_ EAQPL 21_ GPAPT 26_ GAAPP 31_ PGPGP 36_ SDSPE 41_ AAVEK 46_ VEVEL 51_ AGPAT 56_ AEPHE 61_ PPEPP 66_ EGGWG 71_ WLVML 76_ AAMWC 81_ NGSVF 86_ GIQNA 91_ CGVLF 96_ VSMLE 101_ TFGSK 106_ DDDKM 111_ VFKTA 116_ WVGSL 121_ SMGMI 126_ FFCCP 131_ IVSVF 136_ TDLFG 141_ CRKTA 146_ VVGAA 151_ VGFVG 156_ LMSSS 161_ FVSSI 166_ EPLYL 171_ TYGII 176_ FACGC 181_ SFAYQ 186_ PSLVI 191_ LGHYF 196_ KKRLG 201_ LVNGI 206_ VTAGS 211_ SVFTI 216_ LLPLL 221_ LRVLI 226_ DSVGL 231_ FYTLR 236_ VLCIF 241_ MFVLF 246_ LAGFT 251_ YRPLA 256_ TSTKD 261_ KESGG 266_ SGSSL 271_ FSRKK 276_ FSPPK 281_ KIFNF 286_ AIFKV 291_ TAYAV 296_ WAVGI 301_ PLALF 306_ GYFVP 311_ YVHLM 316_ KHVNE 321_ RFQDE 326_ KNKEV 331_ VLMCI 336_ GVTSG 341_ VGRLL 346_ FGRIA 351_ DYVPG 356_ VKKVY 361_ LQVLS 366_ FFFIG 371_ LMSMM 376_ IPLCS 381_ IFGAL 386_ IAVCL 391_ IMGLF 396_ DGCFI 401_ SIMAP 406_ IAFEL 411_ VGAQD 416_ VSQAI 421_ GFLLG 426_ FMSIP 431_ MTVGP 436_ PIAGL 441_ LRDKL 446_ GSYDV 451_ AFYLA 456_ GVPPL 461_ IGGAV 466_ LCFIP 471_ WIHSK 476_ KQREI 481_ SKTTG 486_ KEKME 491_ KMLEN 496_ QNSLL 501_ SSSSG 506_MFKKE
1: Sodium- and proton-independent thyroid hormones and aromatic acids transporter (PubMed:11827462, PubMed:18337592, PubMed:28754537). Mediates both uptake and efflux of 3,5,3'-triiodothyronine (T3) and 3,5,3',5'-tetraiodothyronine (T4) with high affinity, suggesting a role in the homeostasis of thyroid hormone levels (PubMed:18337592). Responsible for low affinity bidirectional transport of the aromatic amino acids, such as phenylalanine, tyrosine, tryptophan and L-3,4-dihydroxyphenylalanine (L-dopa) (PubMed:11827462, PubMed:28754537). Plays an important role in homeostasis of aromatic amino acids (By similarity)