Scavenger receptor class B member 1 (SRB1) (CD36 and LIMPII analogous 1) (CLA-1) (CD36 antigen-like 1) (Collagen type I receptor, thrombospondin receptor-like 1) (SR-BI) (CD antigen CD36)
1_MGCSA 6_ KARWA 11_ AGALG 16_ VAGLL 21_ CAVLG 26_ AVMIV 31_ MVPSL 36_ IKQQV 41_ LKNVR 46_ IDPSS 51_ LSFNM 56_ WKEIP 61_ IPFYL 66_ SVYFF 71_ DVMNP 76_ SEILK 81_ GEKPQ 86_ VRERG 91_ PYVYR 96_ EFRHK 101_ SNITF 106_ NNNDT 111_ VSFLE 116_ YRTFQ 121_ FQPSK 126_ SHGSE 131_ SDYIV 136_ MPNIL 141_ VLGAA 146_ VMMEN 151_ KPMTL 156_ KLIMT 161_ LAFTT 166_ LGERA 171_ FMNRT 176_ VGEIM 181_ WGYKD 186_ PLVNL 191_ INKYF 196_ PGMFP 201_ FKDKF 206_ GLFAE 211_ LNNSD 216_ SGLFT 221_ VFTGV 226_ QNISR 231_ IHLVD 236_ KWNGL 241_ SKVDF 246_ WHSDQ 251_ CNMIN 256_ GTSGQ 261_ MWPPF 266_ MTPES 271_ SLEFY 276_ SPEAC 281_ RSMKL 286_ MYKES 291_ GVFEG 296_ IPTYR 301_ FVAPK 306_ TLFAN 311_ GSIYP 316_ PNEGF 321_ CPCLE 326_ SGIQN 331_ VSTCR 336_ FSAPL 341_ FLSHP 346_ HFLNA 351_ DPVLA 356_ EAVTG 361_ LHPNQ 366_ EAHSL 371_ FLDIH 376_ PVTGI 381_ PMNCS 386_ VKLQL 391_ SLYMK 396_ SVAGI 401_ GQTGK 406_ IEPVV 411_ LPLLW 416_ FAESG 421_ AMEGE 426_ TLHTF 431_ YTQLV 436_ LMPKV 441_ MHYAQ 446_ YVLLA 451_ LGCVL 456_ LLVPV 461_ ICQIR 466_ SQVGA 471_ GQRAA 476_ RADSH 481_ SLACW 486_ GKGAS 491_ DRTLW 496_ PTAAW 501_ SPPPA 506_ AVLRL 511_ CRSGS 516_ GHCWG 521_ LRSTL 526_ ASFAC 531_ RVATT 536_ LPVLE 541_ GLGPS 546_LGGGT
1: Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells (PubMed:12016218, PubMed:12519372, PubMed:21226579). Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux (PubMed:26965621). Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (PubMed:12016218)
2: (Microbial infection) Acts as a receptor for hepatitis C virus in hepatocytes and appears to facilitate its cell entry (PubMed:12356718, PubMed:12913001, PubMed:18000990). Binding between SCARB1 and the hepatitis C virus glycoprotein E2 is independent of the genotype of the viral isolate (PubMed:12356718)
3: (Microbial infection) Mediates uptake of M.fortuitum, E.coli and S.aureus
4: (Microbial infection) Facilitates the entry of human coronavirus SARS-CoV-2 by acting as an entry cofactor through HDL binding