Phospholipase ABHD3 (EC 3.1.1.32) (EC 3.1.1.4) (Abhydrolase domain-containing protein 3)
1_MQRLA 6_ MDLRM 11_ LSREL 16_ SLYLE 21_ HQVRV 26_ GFFGS 31_ GVGLS 36_ LILGF 41_ SVAYA 46_ FYYLS 51_ SIAKK 56_ PQLVT 61_ GGESF 66_ SRFLQ 71_ DHCPV 76_ VTETY 81_ YPTVW 86_ CWEGR 91_ GQTLL 96_ RPFIT 101_ SKPPV 106_ QYRNE 111_ LIKTA 116_ DGGQI 121_ SLDWF 126_ DNDNS 131_ TCYMD 136_ ASTRP 141_ TILLL 146_ PGLTG 151_ TSKES 156_ YILHM 161_ IHLSE 166_ ELGYR 171_ CVVFN 176_ NRGVA 181_ GENLL 186_ TPRTY 191_ CCANT 196_ EDLET 201_ VIHHV 206_ HSLYP 211_ SAPFL 216_ AAGVS 221_ MGGML 226_ LLNYL 231_ GKIGS 236_ KTPLM 241_ AAATF 246_ SVGWN 251_ TFACS 256_ ESLEK 261_ PLNWL 266_ LFNYY 271_ LTTCL 276_ QSSVN 281_ KHRHM 286_ FVKQV 291_ DMDHV 296_ MKAKS 301_ IREFD 306_ KRFTS 311_ VMFGY 316_ QTIDD 321_ YYTDA 326_ SPSPR 331_ LKSVG 336_ IPVLC 341_ LNSVD 346_ DVFSP 351_ SHAIP 356_ IETAK 361_ QNPNV 366_ ALVLT 371_ SYGGH 376_ IGFLE 381_ GIWPR 386_ QSTYM 391_ DRVFK 396_ QFVQA 401_MVEHG
1: Phospholipase that may play a role in phospholipids remodeling. May selectively cleave myristate (C14)-containing phosphatidylcholines through its predominant phospholipase 1 activity, cleaving preferentially acyl groups in sn1 position. In parallel, may have a minor phospholipase 2 activity acting on acyl groups in position sn2. In addition to (C14)-containing phosphatidylcholines, may also act on other medium-chain-containing and oxidatively truncated phospholipids