Cholinephosphotransferase 1 (hCPT1) (EC 2.7.8.2) (AAPT1-like protein) (Diacylglycerol cholinephosphotransferase 1)
1_MAAGA 6_ GAGSA 11_ PRWLR 16_ ALSEP 21_ LSAAQ 26_ LRRLE 31_ EHRYS 36_ AAGVS 41_ LLEPP 46_ LQLYW 51_ TWLLQ 56_ WIPLW 61_ MAPNS 66_ ITLLG 71_ LAVNV 76_ VTTLV 81_ LISYC 86_ PTATE 91_ EAPYW 96_ TYLLC 101_ ALGLF 106_ IYQSL 111_ DAIDG 116_ KQARR 121_ TNSCS 126_ PLGEL 131_ FDHGC 136_ DSLST 141_ VFMAV 146_ GASIA 151_ ARLGT 156_ YPDWF 161_ FFCSF 166_ IGMFV 171_ FYCAH 176_ WQTYV 181_ SGMLR 186_ FGKVD 191_ VTEIQ 196_ IALVI 201_ VFVLS 206_ AFGGA 211_ TMWDY 216_ TIPIL 221_ EIKLK 226_ ILPVL 231_ GFLGG 236_ VIFSC 241_ SNYFH 246_ VILHG 251_ GVGKN 256_ GSTIA 261_ GTSVL 266_ SPGLH 271_ IGLII 276_ ILAIM 281_ IYKKS 286_ ATDVF 291_ EKHPC 296_ LYILM 301_ FGCVF 306_ AKVSQ 311_ KLVVA 316_ HMTKS 321_ ELYLQ 326_ DTVFL 331_ GPGLL 336_ FLDQY 341_ FNNFI 346_ DEYVV 351_ LWMAM 356_ VISSF 361_ DMVIY 366_ FSALC 371_ LQISR 376_ HLHLN 381_ IFKTA 386_ CHQAP 391_ EQVQV 396_ LSSKS 401_HQNNM
1: Catalyzes the final step of de novo phosphatidylcholine (PC) synthesis, i.e. the transfer of choline phosphate from CDP-choline to the free hydroxyl of a diacylglycerol (DAG), producing a PC. It thereby plays a central role in the formation and maintenance of vesicular membranes