Cotranscriptional regulator FAM172A (Protein FAM172A)
1_MSISL 6_ SSLIL 11_ LPIWI 16_ NMAQI 21_ QQGGP 26_ DEKEK 31_ TTALK 36_ DLLSR 41_ IDLDE 46_ LMKKD 51_ EPPLD 56_ FPDTL 61_ EGFEY 66_ AFNEK 71_ GQLRH 76_ IKTGE 81_ PFVFN 86_ YREDL 91_ HRWNQ 96_ KRYEA 101_ LGEII 106_ TKYVY 111_ ELLEK 116_ DCNLK 121_ KVSIP 126_ VDATE 131_ SEPKS 136_ FIFMS 141_ EDALT 146_ NPQKL 151_ MVLIH 156_ GSGVV 161_ RAGQW 166_ ARRLI 171_ INEDL 176_ DSGTQ 181_ IPFIK 186_ RAVAE 191_ GYGVI 196_ VLNPN 201_ ENYIE 206_ VEKPK 211_ IHVQS 216_ SSDSS 221_ DEPAE 226_ KRERK 231_ DKVSK 236_ ETKKR 241_ RDFYE 246_ KYRNP 251_ QREKE 256_ MMQLY 261_ IRENG 266_ SPEEH 271_ AIYVW 276_ DHFIA 281_ QAAAE 286_ NVFFV 291_ AHSYG 296_ GLAFV 301_ ELMIQ 306_ READV 311_ KNKVT 316_ AVALT 321_ DSVHN 326_ VWHQE 331_ AGKTI 336_ REWMR 341_ ENCCN 346_ WVSSS 351_ EPLDT 356_ SVESM 361_ LPDCP 366_ RVSAG 371_ TDRHE 376_ LTSWK 381_ SFPSI 386_ FKFFT 391_ EASEA 396_ KTSSL 401_ KPAVT 406_ RRSHR 411_IKHEE
1: Plays a role in the regulation of alternative splicing, by interacting with AGO2 and CHD7. Seems to be required for stabilizing protein-protein interactions at the chromatin-spliceosome interface. May have hydrolase activity