Solute carrier family 22 member 17 (24p3 receptor) (24p3R) (Brain-type organic cation transporter) (Lipocalin-2 receptor) (Neutrophil gelatinase-associated lipocalin receptor) (NgalR)
1_MASDP 6_ IFTLA 11_ PPLHC 16_ HYGAF 21_ PPNAS 26_ GWEQP 31_ PNASG 36_ VSVAS 41_ AALAA 46_ SAASR 51_ VATST 56_ DPSCS 61_ GFAPP 66_ DFNHC 71_ LKDWD 76_ YNGLP 81_ VLTTN 86_ AIGQW 91_ DLVCD 96_ LGWQV 101_ ILEQI 106_ LFILG 111_ FASGY 116_ LFLGY 121_ PADRF 126_ GRRGI 131_ VLLTL 136_ GLVGP 141_ CGVGG 146_ AAAGS 151_ STGVM 156_ ALRFL 161_ LGFLL 166_ AGVDL 171_ GVYLM 176_ RLELC 181_ DPTQR 186_ LRVAL 191_ AGELV 196_ GVGGH 201_ FLFLG 206_ LALVS 211_ KDWRF 216_ LQRMI 221_ TAPCI 226_ LFLFY 231_ GWPGL 236_ FLESA 241_ RWLIV 246_ KRQIE 251_ EAQSV 256_ LRILA 261_ ERNRP 266_ HGQML 271_ GEEAQ 276_ EALQD 281_ LENTC 286_ PLPAT 291_ SSFSF 296_ ASLLN 301_ YRNIW 306_ KNLLI 311_ LGFTN 316_ FIAHA 321_ IRHCY 326_ QPVGG 331_ GGSPS 336_ DFYLC 341_ SLLAS 346_ GTAAL 351_ ACVFL 356_ GVTVD 361_ RFGRR 366_ GILLL 371_ SMTLT 376_ GIASL 381_ VLLGL 386_ WDCEH 391_ PIFPT 396_ VWAQQ 401_ GNPNR 406_ DLNEA 411_ AITTF 416_ SVLGL 421_ FSSQA 426_ AAILS 431_ TLLAA 436_ EVIPT 441_ TVRGR 446_ GLGLI 451_ MALGA 456_ LGGLS 461_ GPAQR 466_ LHMGH 471_ GAFLQ 476_ HVVLA 481_ ACALL 486_ CILSI 491_ MLLPE 496_ TKRKL 501_ LPEVL 506_ RDGEL 511_ CRRPS 516_ LLRQP 521_ PPTRC 526_ DHVPL 531_LATPN
1: Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis (By similarity)