Sodium-dependent phosphate transporter 1 (Gibbon ape leukemia virus receptor 1) (GLVR-1) (Leukemia virus receptor 1 homolog) (Phosphate transporter 1) (PiT-1) (Solute carrier family 20 member 1)
1_MATLI 6_ TSTTA 11_ ATAAS 16_ GPLVD 21_ YLWML 26_ ILGFI 31_ IAFVL 36_ AFSVG 41_ ANDVA 46_ NSFGT 51_ AVGSG 56_ VVTLK 61_ QACIL 66_ ASIFE 71_ TVGSV 76_ LLGAK 81_ VSETI 86_ RKGLI 91_ DVEMY 96_ NSTQG 101_ LLMAG 106_ SVSAM 111_ FGSAV 116_ WQLVA 121_ SFLKL 126_ PISGT 131_ HCIVG 136_ ATIGF 141_ SLVAK 146_ GQEGV 151_ KWSEL 156_ IKIVM 161_ SWFVS 166_ PLLSG 171_ IMSGI 176_ LFFLV 181_ RAFIL 186_ HKADP 191_ VPNGL 196_ RALPV 201_ FYACT 206_ VGINL 211_ FSIMY 216_ TGAPL 221_ LGFDK 226_ LPLWG 231_ TILIS 236_ VGCAV 241_ FCALI 246_ VWFFV 251_ CPRMK 256_ RKIER 261_ EIKCS 266_ PSESP 271_ LMEKK 276_ NSLKE 281_ DHEET 286_ KLSVG 291_ DIENK 296_ HPVSE 301_ VGPAT 306_ VPLQA 311_ VVEER 316_ TVSFK 321_ LGDLE 326_ EAPER 331_ ERLPS 336_ VDLKE 341_ ETSID 346_ STVNG 351_ AVQLP 356_ NGNLV 361_ QFSQA 366_ VSNQI 371_ NSSGH 376_ YQYHT 381_ VHKDS 386_ GLYKE 391_ LLHKL 396_ HLAKV 401_ GDCMG 406_ DSGDK 411_ PLRRN 416_ NSYTS 421_ YTMAI 426_ CGMPL 431_ DSFRA 436_ KEGEQ 441_ KGEEM 446_ EKLTW 451_ PNADS 456_ KKRIR 461_ MDSYT 466_ SYCNA 471_ VSDLH 476_ SASEI 481_ DMSVK 486_ AEMGL 491_ GDRKG 496_ SNGSL 501_ EEWYD 506_ QDKPE 511_ VSLLF 516_ QFLQI 521_ LTACF 526_ GSFAH 531_ GGNDV 536_ SNAIG 541_ PLVAL 546_ YLVYD 551_ TGDVS 556_ SKVAT 561_ PIWLL 566_ LYGGV 571_ GICVG 576_ LWVWG 581_ RRVIQ 586_ TMGKD 591_ LTPIT 596_ PSSGF 601_ SIELA 606_ SALTV 611_ VIASN 616_ IGLPI 621_ STTHC 626_ KVGSV 631_ VSVGW 636_ LRSKK 641_ AVDWR 646_ LFRNI 651_ FMAWF 656_ VTVPI 661_ SGVIS 666_ AAIMA 671_IFRYV
1: Sodium-phosphate symporter which preferentially transports the monovalent form of phosphate with a stoichiometry of two sodium ions per phosphate ion (PubMed:11009570, PubMed:16790504, PubMed:17494632, PubMed:19726692, PubMed:7929240, PubMed:8041748). May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification (PubMed:11009570). Essential for cell proliferation but this function is independent of its phosphate transporter activity (PubMed:19726692)
2: (Microbial infection) May function as a retroviral receptor as it confers human cells susceptibility to infection to Gibbon Ape Leukemia Virus (GaLV), Simian sarcoma-associated virus (SSAV) and Feline leukemia virus subgroup B (FeLV-B) as well as 10A1 murine leukemia virus (10A1 MLV)