Protein LTO1 homolog (Oral cancer-overexpressed protein 1) (Tumor-amplified and overexpressed sequence 1)
1_MAGSQ 6_ DIFDA 11_ IVMAD 16_ ERFHG 21_ EGYRE 26_ GYEEG 31_ SSLGV 36_ MEGRQ 41_ HGTLH 46_ GAKIG 51_ SEIGC 56_ YQGFA 61_ FAWKC 66_ LLHSC 71_ TTEKD 76_ SRKMK 81_ VLESL 86_ IGMIQ 91_ KFPYD 96_ DPTYD 101_ KLHED 106_ LDKIR 111_ GKFKQ 116_ FCSLL 121_ NVQPD 126_ FKISA 131_EGSGL
1: The complex LTO1:YAE1 functions as a target specific adapter that probably recruits apo-ABCE1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery (PubMed:26182403). May be required for biogenesis of the large ribosomal subunit and initiation of translation (PubMed:23318452). May play a role in the regulation of proline metabolism and ROS production (PubMed:24930674)