AFG1-like ATPase (Lactation elevated protein 1) (EC 3.6.-.-) (Protein AFG1 homolog)
1_MAASW 6_ SLLVT 11_ LRPLA 16_ QSPLR 21_ GRCVG 26_ CGAWA 31_ AALAP 36_ LATAP 41_ GKPFW 46_ KAYTV 51_ QTSES 56_ MTPTA 61_ TSETY 66_ LKALA 71_ VCHGP 76_ LDHYD 81_ FLIKA 86_ HELKD 91_ DEHQR 96_ RVIQC 101_ LQKLH 106_ EDLKG 111_ YNIEA 116_ EGLFS 121_ KLFSR 126_ SKPPR 131_ GLYVY 136_ GDVGT 141_ GKTMV 146_ MDMFY 151_ AYVEM 156_ KRKKR 161_ VHFHG 166_ FMLDV 171_ HKRIH 176_ RLKQS 181_ LPKRK 186_ PGFMA 191_ KSYDP 196_ IAPIA 201_ EEISE 206_ EACLL 211_ CFDEF 216_ QVTDI 221_ ADAMI 226_ LKQLF 231_ ENLFK 236_ NGVVV 241_ VATSN 246_ RPPED 251_ LYKNG 256_ LQRAN 261_ FVPFI 266_ AVLKE 271_ YCNTV 276_ QLDSG 281_ IDYRK 286_ RELPA 291_ AGKLY 296_ YLTSE 301_ ADVEA 306_ VMDKL 311_ FDELA 316_ QKQND 321_ LTRPR 326_ ILKVQ 331_ GRELR 336_ LNKAC 341_ GTVAD 346_ CTFEE 351_ LCERP 356_ LGASD 361_ YLELS 366_ KNFDT 371_ IFLRN 376_ IPQFT 381_ LANRT 386_ QGRRF 391_ ITLID 396_ NFYDL 401_ KVRII 406_ CSAST 411_ PISSL 416_ FLHQH 421_ HDSEL 426_ EQSRI 431_ LMDDL 436_ GLSQD 441_ SAEGL 446_ SMFTG 451_ EEEIF 456_ AFQRT 461_ ISRLT 466_ EMQTE 471_ QYWNE 476_GDRTK
1: Putative mitochondrial ATPase. Plays a role in mitochondrial morphology and mitochondrial protein metabolism. Promotes degradation of excess nuclear-encoded complex IV subunits (COX4I1, COX5A and COX6A1) and normal activity of complexes III and IV of the respiratory chain (PubMed:26759378, PubMed:27323408). Mediates mitochondrial translocation of TP53 and its transcription-independent apoptosis in response to genotoxic stress (PubMed:27323408)