Chromosome transmission fidelity protein 18 homolog (hCTF18) (CHL12)
1_MEDYE 6_ QELCG 11_ VEDDF 16_ HNQFA 21_ AELEV 26_ LAELE 31_ GASTP 36_ SPSGV 41_ PLFTA 46_ GRPPR 51_ TFEEA 56_ LARGD 61_ AASSP 66_ APAAS 71_ VGSSQ 76_ GGARK 81_ RQVDA 86_ DLQPA 91_ GSLPH 96_ APRIK 101_ RPRLQ 106_ VVKRL 111_ NFRSE 116_ EMEEP 121_ PPPDS 126_ SPTDI 131_ TPPPS 136_ PEDLA 141_ ELWGH 146_ GVSEA 151_ AADVG 156_ LTRAS 161_ PAARN 166_ PVLRR 171_ PPILE 176_ DYVHV 181_ TSTEG 186_ VRAYL 191_ VLRAD 196_ PMAPG 201_ VQGSL 206_ LHVPW 211_ RGGGQ 216_ LDLLG 221_ VSLAS 226_ LKKQV 231_ DGERR 236_ ERLLQ 241_ EAQKL 246_ SDTLH 251_ SLRSG 256_ EEEAA 261_ QPLGA 266_ PEEEP 271_ TDGQD 276_ ASSHC 281_ LWVDE 286_ FAPRH 291_ YTELL 296_ SDDFT 301_ NRCLL 306_ KWLKL 311_ WDLVV 316_ FGHER 321_ PSRKP 326_ RPSVE 331_ PARVS 336_ KEATA 341_ PGKWK 346_ SHEQV 351_ LEEML 356_ EAGLD 361_ PSQRP 366_ KQKVA 371_ LLCGP 376_ PGLGK 381_ TTLAH 386_ VIARH 391_ AGYSV 396_ VEMNA 401_ SDDRS 406_ PEVFR 411_ TRIEA 416_ ATQME 421_ SVLGA 426_ GGKPN 431_ CLVID 436_ EIDGA 441_ PVAAI 446_ NVLLS 451_ ILNRK 456_ GPQEV 461_ GPQGP 466_ AVPSG 471_ GGRRR 476_ RAEGG 481_ LLMRP 486_ IICIC 491_ NDQFA 496_ PSLRQ 501_ LKQQA 506_ FLLHF 511_ PPTLP 516_ SRLVQ 521_ RLQEV 526_ SLRQG 531_ MRADP 536_ GVLAA 541_ LCEKT 546_ DNDIR 551_ ACINT 556_ LQFLY 561_ SRGQR 566_ ELSVR 571_ DVQAT 576_ RVGLK 581_ DQRRG 586_ LFSVW 591_ QEVFQ 596_ LPRAQ 601_ RRRVG 606_ QDPAL 611_ PADTL 616_ LLGDG 621_ DAGSL 626_ TSASQ 631_ RFYRV 636_ LHAAA 641_ SAGEH 646_ EKVVQ 651_ GLFDN 656_ FLRLR 661_ LRDSS 666_ LGAVC 671_ VALDW 676_ LAFDD 681_ LLAGA 686_ AHHSQ 691_ SFQLL 696_ RYPPF 701_ LPVAF 706_ HVLFA 711_ SSHTP 716_ RITFP 721_ SSQQE 726_ AQNRM 731_ SQMRN 736_ LIQTL 741_ VSGIA 746_ PATRS 751_ RATPQ 756_ ALLLD 761_ ALCLL 766_ LDILA 771_ PKLRP 776_ VSTQL 781_ YSTRE 786_ KQQLA 791_ SLVGT 796_ MLAYS 801_ LTYRQ 806_ ERTPD 811_ GQYIY 816_ RLEPN 821_ VEELC 826_ RFPEL 831_ PARKP 836_ LTYQT 841_ KQLIA 846_ REIEV 851_ EKMRR 856_ AEASA 861_ RVENS 866_ PQVDG 871_ SPPGL 876_ EGLLG 881_ GIGEK 886_ GVHRP 891_ APRNH 896_ EQRLE 901_ HIMRR 906_ AAREE 911_ QPEKD 916_ FFGRV 921_ VVRST 926_ AVPSA 931_ GDTAP 936_ EQDSV 941_ ERRMG 946_ TAVGR 951_ SEVWF 956_ RFNEG 961_ VSNAV 966_RRSLY
1: Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A (RPA) and by proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. Interacts with and stimulates DNA polymerase POLH. During DNA repair synthesis, involved in loading DNA polymerase POLE at the sites of local damage (PubMed:20227374)