Gene name: CPLX3

Uniprot entry:

Q8WVH0

Protein names:

Complexin-3 (Complexin III) (CPX III)

Protein sequence:

1_MAFMV 6_ KTMVG 11_ GQLKN 16_ LTGSL 21_ GGGED 26_ KGDGD 31_ KSAAE 36_ AQGMS 41_ REEYE 46_ EYQKQ 51_ LVEEK 56_ MERDA 61_ QFTQR 66_ KAERA 71_ TLRSH 76_ FRDKY 81_ RLPKN 86_ ETDES 91_ QIQMA 96_ GGDVE 101_ LPREL 106_ AKMIE 111_ EDTEE 116_ EEEKA 121_ SVLGQ 126_ LASLP 131_ GLNLG 136_ SLKDK 141_ AQATL 146_ GDLKQ 151_SAEKC

Protein annotations

Protein functions:

1: Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion (By similarity). Required for the maintenance of synaptic ultrastructure in the adult retina (By similarity). Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina (By similarity). Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca(2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca(2+) vesicle release (By similarity)