Small integral membrane protein 4
1_MFTRA 6_ QVRRI 11_ LQRVP 16_ GKQRF 21_ GIYRF 26_ LPFFF 31_ VLGGT 36_ MEWIM 41_ IKVRV 46_ GQETF 51_ YDVYR 56_ RKASE 61_RQYQR
1: Required for the assembly and stability of the mitochondrial ubiquinol-cytochrome c reductase complex (complex III (CIII) or cytochrome b-c1 complex), a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain (ETC) which drives oxidative phosphorylation (By similarity). Mediates early complex III biogenesis (By similarity). Participates in regulating the levels of electron transport chain proteins, and therefore energy supply, in response to changes in energy demand (By similarity). Also involved in the first steps of cytochrome c oxidase complex (complex IV) assembly (PubMed:34969438)