Gene name: ANKRD49

Uniprot entry:

Q8WVL7

Protein names:

Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor)

Protein sequence:

1_MEKEK 6_ GNDDG 11_ IPDQE 16_ NSLDF 21_ SEHFN 26_ QLELL 31_ ETHGH 36_ LIPTG 41_ TQSLW 46_ VGNSD 51_ EDEEQ 56_ DDKNE 61_ EWYRL 66_ QEKKM 71_ EKDPS 76_ RLLLW 81_ AAEKN 86_ RLTTV 91_ RRLLS 96_ EKATH 101_ VNTRD 106_ EDEYT 111_ PLHRA 116_ AYSGH 121_ LDIVQ 126_ ELIAQ 131_ GADVH 136_ AVTVD 141_ GWTPL 146_ HSACK 151_ WNNTR 156_ VASFL 161_ LQHDA 166_ DINAQ 171_ TKGLL 176_ TPLHL 181_ AAGNR 186_ DSKDT 191_ LELLL 196_ MNRYV 201_ KPGLK 206_ NNLEE 211_ TAFDI 216_ ARRTS 221_ IYHYL 226_ FEIVE 231_GCTNS

Protein annotations

Protein functions:

1: Induces HBG1 expression (PubMed:11162141, PubMed:16131492). May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF-kappaB pathway (By similarity)