Gene name: MAIP1

Uniprot entry:

Q8WWC4

Protein names:

m-AAA protease-interacting protein 1, mitochondrial (Matrix AAA peptidase-interacting protein 1)

Protein sequence:

1_MALAA 6_ RLLPQ 11_ FLHSR 16_ SLPCG 21_ AVRLR 26_ TPAVA 31_ EVRLP 36_ SATLC 41_ YFCRC 46_ RLGLG 51_ AALFP 56_ RSARA 61_ LAASA 66_ LPAQG 71_ SRWPV 76_ LSSPG 81_ LPAAF 86_ ASFPA 91_ CPQRS 96_ YSTEE 101_ KPQQH 106_ QKTKM 111_ IVLGF 116_ SNPIN 121_ WVRTR 126_ IKAFL 131_ IWAYF 136_ DKEFS 141_ ITEFS 146_ EGAKQ 151_ AFAHV 156_ SKLLS 161_ QCKFD 166_ LLEEL 171_ VAKEV 176_ LHALK 181_ EKVTS 186_ LPDNH 191_ KNALA 196_ ANIDE 201_ IVFTS 206_ TGDIS 211_ IYYDE 216_ KGRKF 221_ VNILM 226_ CFWYL 231_ TSANI 236_ PSETL 241_ RGASV 246_ FQVKL 251_ GNQNV 256_ ETKQL 261_ LSASY 266_ EFQRE 271_ FTQGV 276_ KPDWT 281_ IARIE 286_HSKLL

Protein annotations

Protein functions:

1: Promotes sorting of SMDT1/EMRE in mitochondria by ensuring its maturation (PubMed:27642048). Interacts with the transit peptide region of SMDT1/EMRE precursor protein in the mitochondrial matrix, leading to protect it against protein degradation by YME1L1, thereby ensuring SMDT1/EMRE maturation by the mitochondrial processing peptidase (PMPCA and PMPCB) (PubMed:27642048)