PH-interacting protein (PHIP) (DDB1- and CUL4-associated factor 14) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11)
1_MSCER 6_ KGLSE 11_ LRSEL 16_ YFLIA 21_ RFLED 26_ GPCQQ 31_ AAQVL 36_ IREVA 41_ EKELL 46_ PRRTD 51_ WTGKE 56_ HPRTY 61_ QNLVK 66_ YYRHL 71_ APDHL 76_ LQICH 81_ RLGPL 86_ LEQEI 91_ PQSVP 96_ GVQTL 101_ LGAGR 106_ QSLLR 111_ TNKSC 116_ KHVVW 121_ KGSAL 126_ AALHC 131_ GRPPE 136_ SPVNY 141_ GSPPS 146_ IADTL 151_ FSRKL 156_ NGKYR 161_ LERLV 166_ PTAVY 171_ QHMKM 176_ HKRIL 181_ GHLSS 186_ VYCVT 191_ FDRTG 196_ RRIFT 201_ GSDDC 206_ LVKIW 211_ ATDDG 216_ RLLAT 221_ LRGHA 226_ AEISD 231_ MAVNY 236_ ENTMI 241_ AAGSC 246_ DKMIR 251_ VWCLR 256_ TCAPL 261_ AVLQG 266_ HSASI 271_ TSLQF 276_ SPLCS 281_ GSKRY 286_ LSSTG 291_ ADGTI 296_ CFWLW 301_ DAGTL 306_ KINPR 311_ PAKFT 316_ ERPRP 321_ GVQMI 326_ CSSFS 331_ AGGMF 336_ LATGS 341_ TDHII 346_ RVYFF 351_ GSGQP 356_ EKISE 361_ LEFHT 366_ DKVDS 371_ IQFSN 376_ TSNRF 381_ VSGSR 386_ DGTAR 391_ IWQFK 396_ RREWK 401_ SILLD 406_ MATRP 411_ AGQNL 416_ QGIED 421_ KITKM 426_ KVTMV 431_ AWDRH 436_ DNTVI 441_ TAVNN 446_ MTLKV 451_ WNSYT 456_ GQLIH 461_ VLMGH 466_ EDEVF 471_ VLEPH 476_ PFDPR 481_ VLFSA 486_ GHDGN 491_ VIVWD 496_ LARGV 501_ KIRSY 506_ FNMIE 511_ GQGHG 516_ AVFDC 521_ KCSPD 526_ GQHFA 531_ CTDSH 536_ GHLLI 541_ FGFGS 546_ SSKYD 551_ KIADQ 556_ MFFHS 561_ DYRPL 566_ IRDAN 571_ NFVLD 576_ EQTQQ 581_ APHLM 586_ PPPFL 591_ VDVDG 596_ NPHPS 601_ RYQRL 606_ VPGRE 611_ NCREE 616_ QLIPQ 621_ MGVTS 626_ SGLNQ 631_ VLSQQ 636_ ANQEI 641_ SPLDS 646_ MIQRL 651_ QQEQD 656_ LRRSG 661_ EAVIS 666_ NTSRL 671_ SRGSI 676_ SSTSE 681_ VHSPP 686_ NVGLR 691_ RSGQI 696_ EGVRQ 701_ MHSNA 706_ PRSEI 711_ ATERD 716_ LVAWS 721_ RRVVV 726_ PELSA 731_ GVASR 736_ QEEWR 741_ TAKGE 746_ EEIKT 751_ YRSEE 756_ KRKHL 761_ TVPKE 766_ NKIPT 771_ VSKNH 776_ AHEHF 781_ LDLGE 786_ SKKQQ 791_ TNQHN 796_ YRTRS 801_ ALEET 806_ PRPSE 811_ EIENG 816_ SSSSD 821_ EGEVV 826_ AVSGG 831_ TSEEE 836_ ERAWH 841_ SDGSS 846_ SDYSS 851_ DYSDW 856_ TADAG 861_ INLQP 866_ PKKVP 871_ KNKTK 876_ KAESS 881_ SDEEE 886_ ESEKQ 891_ KQKQI 896_ KKEKK 901_ KVNEE 906_ KDGPI 911_ SPKKK 916_ KPKER 921_ KQKRL 926_ AVGEL 931_ TENGL 936_ TLEEW 941_ LPSTW 946_ ITDTI 951_ PRRCP 956_ FVPQM 961_ GDEVY 966_ YFRQG 971_ HEAYV 976_ EMARK 981_ NKIYS 986_ INPKK 991_ QPWHK 996_ MELRE 1001_ QELMK 1006_ IVGIK 1011_ YEVGL 1016_ PTLCC 1021_ LKLAF 1026_ LDPDT 1031_ GKLTG 1036_ GSFTM 1041_ KYHDM 1046_ PDVID 1051_ FLVLR 1056_ QQFDD 1061_ AKYRR 1066_ WNIGD 1071_ RFRSV 1076_ IDDAW 1081_ WFGTI 1086_ ESQEP 1091_ LQLEY 1096_ PDSLF 1101_ QCYNV 1106_ CWDNG 1111_ DTEKM 1116_ SPWDM 1121_ ELIPN 1126_ NAVFP 1131_ EELGT 1136_ SVPLT 1141_ DGECR 1146_ SLIYK 1151_ PLDGE 1156_ WGTNP 1161_ RDEEC 1166_ ERIVA 1171_ GINQL 1176_ MTLDI 1181_ ASAFV 1186_ APVDL 1191_ QAYPM 1196_ YCTVV 1201_ AYPTD 1206_ LSTIK 1211_ QRLEN 1216_ RFYRR 1221_ VSSLM 1226_ WEVRY 1231_ IEHNT 1236_ RTFNE 1241_ PGSPI 1246_ VKSAK 1251_ FVTDL 1256_ LLHFI 1261_ KDQTC 1266_ YNIIP 1271_ LYNSM 1276_ KKKVL 1281_ SDSED 1286_ EEKDA 1291_ DVPGT 1296_ STRKR 1301_ KDHQP 1306_ RRRLR 1311_ NRAQS 1316_ YDIQA 1321_ WKKQC 1326_ EELLN 1331_ LIFQC 1336_ EDSEP 1341_ FRQPV 1346_ DLLEY 1351_ PDYRD 1356_ IIDTP 1361_ MDFAT 1366_ VRETL 1371_ EAGNY 1376_ ESPME 1381_ LCKDV 1386_ RLIFS 1391_ NSKAY 1396_ TPSKR 1401_ SRIYS 1406_ MSLRL 1411_ SAFFE 1416_ EHISS 1421_ VLSDY 1426_ KSALR 1431_ FHKRN 1436_ TITKR 1441_ RKKRN 1446_ RSSSV 1451_ SSSAA 1456_ SSPER 1461_ KKRIL 1466_ KPQLK 1471_ SESST 1476_ SAFST 1481_ PTRSI 1486_ PPRHN 1491_ AAQIN 1496_ GKTES 1501_ SSVVR 1506_ TRSNR 1511_ VVVDP 1516_ VVTEQ 1521_ PSTSS 1526_ AAKTF 1531_ ITKAN 1536_ ASAIP 1541_ GKTIL 1546_ ENSVK 1551_ HSKAL 1556_ NTLSS 1561_ PGQSS 1566_ FSHGT 1571_ RNNSA 1576_ KENME 1581_ KEKPV 1586_ KRKMK 1591_ SSVLP 1596_ KASTL 1601_ SKSSA 1606_ VIEQG 1611_ DCKNN 1616_ ALVPG 1621_ TIQVN 1626_ GHGGQ 1631_ PSKLV 1636_ KRGPG 1641_ RKPKV 1646_ EVNTN 1651_ SGEII 1656_ HKKRG 1661_ RKPKK 1666_ LQYAK 1671_ PEDLE 1676_ QNNVH 1681_ PIRDE 1686_ VLPSS 1691_ TCNFL 1696_ SETNN 1701_ VKEDL 1706_ LQKKN 1711_ RGGRK 1716_ PKRKM 1721_ KTQKL 1726_ DADLL 1731_ VPASV 1736_ KVLRR 1741_ SNRKK 1746_ IDDPI 1751_ DEEEE 1756_ FEELK 1761_ GSEPH 1766_ MRTRN 1771_ QGRRT 1776_ AFYNE 1781_ DDSEE 1786_ EQRQL 1791_ LFEDT 1796_ SLTFG 1801_ TSSRG 1806_ RVRKL 1811_ TEKAK 1816_ANLIG
1: Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization