U4/U6 small nuclear ribonucleoprotein Prp31 (Pre-mRNA-processing factor 31) (Serologically defined breast cancer antigen NY-BR-99) (U4/U6 snRNP 61 kDa protein) (Protein 61K) (hPrp31)
1_MSLAD 6_ ELLAD 11_ LEEAA 16_ EEEEG 21_ GSYGE 26_ EEEEP 31_ AIEDV 36_ QEETQ 41_ LDLSG 46_ DSVKT 51_ IAKLW 56_ DSKMF 61_ AEIMM 66_ KIEEY 71_ ISKQA 76_ KASEV 81_ MGPVE 86_ AAPEY 91_ RVIVD 96_ ANNLT 101_ VEIEN 106_ ELNII 111_ HKFIR 116_ DKYSK 121_ RFPEL 126_ ESLVP 131_ NALDY 136_ IRTVK 141_ ELGNS 146_ LDKCK 151_ NNENL 156_ QQILT 161_ NATIM 166_ VVSVT 171_ ASTTQ 176_ GQQLS 181_ EEELE 186_ RLEEA 191_ CDMAL 196_ ELNAS 201_ KHRIY 206_ EYVES 211_ RMSFI 216_ APNLS 221_ IIIGA 226_ STAAK 231_ IMGVA 236_ GGLTN 241_ LSKMP 246_ ACNIM 251_ LLGAQ 256_ RKTLS 261_ GFSST 266_ SVLPH 271_ TGYIY 276_ HSDIV 281_ QSLPP 286_ DLRRK 291_ AARLV 296_ AAKCT 301_ LAARV 306_ DSFHE 311_ STEGK 316_ VGYEL 321_ KDEIE 326_ RKFDK 331_ WQEPP 336_ PVKQV 341_ KPLPA 346_ PLDGQ 351_ RKKRG 356_ GRRYR 361_ KMKER 366_ LGLTE 371_ IRKQA 376_ NRMSF 381_ GEIEE 386_ DAYQE 391_ DLGFS 396_ LGHLG 401_ KSGSG 406_ RVRQT 411_ QVNEA 416_ TKARI 421_ SKTLQ 426_ RTLQK 431_ QSVVY 436_ GGKST 441_ IRDRS 446_ SGTAS 451_ SVAFT 456_ PLQGL 461_ EIVNP 466_ QAAEK 471_ KVAEA 476_ NQKYF 481_ SSMAE 486_ FLKVK 491_GEKSG
1: Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11867543, PubMed:20118938, PubMed:28781166). Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome (PubMed:11867543)