Interleukin-1 family member 10 (IL-1F10) (Family of interleukin 1-theta) (FIL1 theta) (Interleukin-1 HY2) (IL-1HY2) (Interleukin-1 theta) (IL-1 theta) (Interleukin-38) (IL-38)
1_MCSLP 6_ MARYY 11_ IIKYA 16_ DQKAL 21_ YTRDG 26_ QLLVG 31_ DPVAD 36_ NCCAE 41_ KICIL 46_ PNRGL 51_ ARTKV 56_ PIFLG 61_ IQGGS 66_ RCLAC 71_ VETEE 76_ GPSLQ 81_ LEDVN 86_ IEELY 91_ KGGEE 96_ ATRFT 101_ FFQSS 106_ SGSAF 111_ RLEAA 116_ AWPGW 121_ FLCGP 126_ AEPQQ 131_ PVQLT 136_ KESEP 141_ SARTK 146_FYFEQ
1: Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2