Gene name: NLRP7

Uniprot entry:

Q8WX94

Protein names:

NACHT, LRR and PYD domains-containing protein 7 (Nucleotide-binding oligomerization domain protein 12) (PYRIN-containing APAF1-like protein 3)

Protein sequence:

1_MTSPQ 6_ LEWTL 11_ QTLLE 16_ QLNED 21_ ELKSF 26_ KSLLW 31_ AFPLE 36_ DVLQK 41_ TPWSE 46_ VEEAD 51_ GKKLA 56_ EILVN 61_ TSSEN 66_ WIRNA 71_ TVNIL 76_ EEMNL 81_ TELCK 86_ MAKAE 91_ MMEDG 96_ QVQEI 101_ DNPEL 106_ GDAEE 111_ DSELA 116_ KPGEK 121_ EGWRN 126_ SMEKQ 131_ SLVWK 136_ NTFWQ 141_ GDIDN 146_ FHDDV 151_ TLRNQ 156_ RFIPF 161_ LNPRT 166_ PRKLT 171_ PYTVV 176_ LHGPA 181_ GVGKT 186_ TLAKK 191_ CMLDW 196_ TDCNL 201_ SPTLR 206_ YAFYL 211_ SCKEL 216_ SRMGP 221_ CSFAE 226_ LISKD 231_ WPELQ 236_ DDIPS 241_ ILAQA 246_ QRILF 251_ VVDGL 256_ DELKV 261_ PPGAL 266_ IQDIC 271_ GDWEK 276_ KKPVP 281_ VLLGS 286_ LLKRK 291_ MLPRA 296_ ALLVT 301_ TRPRA 306_ LRDLQ 311_ LLAQQ 316_ PIYVR 321_ VEGFL 326_ EEDRR 331_ AYFLR 336_ HFGDE 341_ DQAMR 346_ AFELM 351_ RSNAA 356_ LFQLG 361_ SAPAV 366_ CWIVC 371_ TTLKL 376_ QMEKG 381_ EDPVP 386_ TCLTR 391_ TGLFL 396_ RFLCS 401_ RFPQG 406_ AQLRG 411_ ALRTL 416_ SLLAA 421_ QGLWA 426_ QMSVF 431_ HREDL 436_ ERLGV 441_ QESDL 446_ RLFLD 451_ GDILR 456_ QDRVS 461_ KGCYS 466_ FIHLS 471_ FQQFL 476_ TALFY 481_ ALEKE 486_ EGEDR 491_ DGHAW 496_ DIGDV 501_ QKLLS 506_ GEERL 511_ KNPDL 516_ IQVGH 521_ FLFGL 526_ ANEKR 531_ AKELE 536_ ATFGC 541_ RMSPD 546_ IKQEL 551_ LQCKA 556_ HLHAN 561_ KPLSV 566_ TDLKE 571_ VLGCL 576_ YESQE 581_ EELAK 586_ VVVAP 591_ FKEIS 596_ IHLTN 601_ TSEVM 606_ HCSFS 611_ LKHCQ 616_ DLQKL 621_ SLQVA 626_ KGVFL 631_ ENYMD 636_ FELDI 641_ EFERC 646_ TYLTI 651_ PNWAR 656_ QDLRS 661_ LRLWT 666_ DFCSL 671_ FSSNS 676_ NLKFL 681_ EVKQS 686_ FLSDS 691_ SVRIL 696_ CDHVT 701_ RSTCH 706_ LQKVE 711_ IKNVT 716_ PDTAY 721_ RDFCL 726_ AFIGK 731_ KTLTH 736_ LTLAG 741_ HIEWE 746_ RTMML 751_ MLCDL 756_ LRNHK 761_ CNLQY 766_ LRLGG 771_ HCATP 776_ EQWAE 781_ FFYVL 786_ KANQS 791_ LKHLR 796_ LSANV 801_ LLDEG 806_ AMLLY 811_ KTMTR 816_ PKHFL 821_ QMLSL 826_ ENCRL 831_ TEASC 836_ KDLAA 841_ VLVVS 846_ KKLTH 851_ LCLAK 856_ NPIGD 861_ TGVKF 866_ LCEGL 871_ SYPDC 876_ KLQTL 881_ VLQQC 886_ SITKL 891_ GCRYL 896_ SEALQ 901_ EACSL 906_ TNLDL 911_ SINQI 916_ ARGLW 921_ ILCQA 926_ LENPN 931_ CNLKH 936_ LRLKT 941_ YETNL 946_ EIKKL 951_ LEEVK 956_ EKNPK 961_ LTIDC 966_ NASGA 971_TAPPC

Protein annotations

Protein functions:

1: Inhibits CASP1/caspase-1-dependent IL1B secretion