Protein N-lysine methyltransferase METTL21A (EC 2.1.1.-) (HSPA lysine methyltransferase) (HSPA-KMT) (Hepatocellular carcinoma-associated antigen 557b) (Methyltransferase-like protein 21A)
1_MALVP 6_ YEETT 11_ EFGLQ 16_ KFHKP 21_ LATFS 26_ FANHT 31_ IQIRQ 36_ DWRHL 41_ GVAAV 46_ VWDAA 51_ IVLST 56_ YLEMG 61_ AVELR 66_ GRSAV 71_ ELGAG 76_ TGLVG 81_ IVAAL 86_ LGAHV 91_ TITDR 96_ KVALE 101_ FLKSN 106_ VQANL 111_ PPHIQ 116_ TKTVV 121_ KELTW 126_ GQNLG 131_ SFSPG 136_ EFDLI 141_ LGADI 146_ IYLEE 151_ TFTDL 156_ LQTLE 161_ HLCSN 166_ HSVIL 171_ LACRI 176_ RYERD 181_ NNFLA 186_ MLERQ 191_ FTVRK 196_ VHYDP 201_ EKDVH 206_ IYEAQ 211_KRNQK
1: Protein-lysine methyltransferase that selectively trimethylates residues in heat shock protein 70 (HSP70) family members. Contributes to the in vivo trimethylation of Lys residues in HSPA1 and HSPA8. In vitro methylates 'Lys-561' in HSPA1, 'Lys-564' in HSPA2, 'Lys-585' in HSPA5, 'Lys-563' in HSPA6 and 'Lys-561' in HSPA8