DNA-binding death effector domain-containing protein 2 (DED-containing protein FLAME-3) (FADD-like anti-apoptotic molecule 3)
1_MALSG 6_ STPAP 11_ CWEED 16_ ECLDY 21_ YGMLS 26_ LHRMF 31_ EVVGG 36_ QLTEC 41_ ELELL 46_ AFLLD 51_ EAPGA 56_ AGGLA 61_ RARSG 66_ LELLL 71_ ELERR 76_ GQCDE 81_ SNLRL 86_ LGQLL 91_ RVLAR 96_ HDLLP 101_ HLARK 106_ RRRPV 111_ SPERY 116_ SYGTS 121_ SSSKR 126_ TEGSC 131_ RRRRQ 136_ SSSSA 141_ NSQQG 146_ QWETG 151_ SPPTK 156_ RQRRS 161_ RGRPS 166_ GGARR 171_ RRRGA 176_ PAAPQ 181_ QQSEP 186_ ARPSS 191_ EGKVT 196_ CDIRL 201_ RVRAE 206_ YCEHG 211_ PALEQ 216_ GVASR 221_ RPQAL 226_ ARQLD 231_ VFGQA 236_ TAVLR 241_ SRDLG 246_ SVVCD 251_ IKFSE 256_ LSYLD 261_ AFWGD 266_ YLSGA 271_ LLQAL 276_ RGVFL 281_ TEALR 286_ EAVGR 291_ EAVRL 296_ LVSVD 301_ EADYE 306_ AGRRR 311_ LLLME 316_ EEGGR 321_RPTEA
1: May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. May regulate degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3