Voltage-dependent calcium channel gamma-8 subunit (Neuronal voltage-gated calcium channel gamma-8 subunit) (Transmembrane AMPAR regulatory protein gamma-8) (TARP gamma-8)
1_MESLK 6_ RWNEE 11_ RGLWC 16_ EKGVQ 21_ VLLTT 26_ VGAFA 31_ AFGLM 36_ TIAIS 41_ TDYWL 46_ YTRAL 51_ ICNTT 56_ NLTAG 61_ GDDGT 66_ PHRGG 71_ GGASE 76_ KKDPG 81_ GLTHS 86_ GLWRI 91_ CCLEG 96_ LKRGV 101_ CVKIN 106_ HFPED 111_ TDYDH 116_ DSAEY 121_ LLRVV 126_ RASSI 131_ FPILS 136_ AILLL 141_ LGGVC 146_ VAASR 151_ VYKSK 156_ RNIIL 161_ GAGIL 166_ FVAAG 171_ LSNII 176_ GVIVY 181_ ISANA 186_ GEPGP 191_ KRDEE 196_ KKNHY 201_ SYGWS 206_ FYFGG 211_ LSFIL 216_ AEVIG 221_ VLAVN 226_ IYIER 231_ SREAH 236_ CQSRS 241_ DLLKA 246_ GGGAG 251_ GSGGS 256_ GPSAI 261_ LRLPS 266_ YRFRY 271_ RRRSR 276_ SSSRS 281_ SEPSP 286_ SRDAS 291_ PGGPG 296_ GPGFA 301_ STDIS 306_ MYTLS 311_ RDPSK 316_ GSVAA 321_ GLAGA 326_ GGGGG 331_ GAVGA 336_ FGGAA 341_ GGAGG 346_ GGGGG 351_ GGAGA 356_ ERDRG 361_ GASGF 366_ LTLHN 371_ AFPKE 376_ AGGGV 381_ TVTVT 386_ GPPAP 391_ PAPAP 396_ PAPSA 401_ PAPGT 406_ LAKEA 411_ AASNT 416_NTLNR
1: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits