Nanos homolog 1 (NOS-1) (EC_Rep1a)
1_MEAFP 6_ WAPRS 11_ PRRGR 16_ APPPM 21_ ALVPS 26_ ARYVS 31_ APGPA 36_ HPQPF 41_ SSWND 46_ YLGLA 51_ TLITK 56_ AVDGE 61_ PRFGC 66_ ARGGN 71_ GGGGS 76_ PPSSS 81_ SSSCC 86_ SPHTG 91_ AGPGA 96_ LGPAL 101_ GPPDY 106_ DEDDD 111_ DDSDE 116_ PGSRG 121_ RYLGS 126_ ALELR 131_ ALELC 136_ AGPAE 141_ AGLLE 146_ ERFAE 151_ LSPFA 156_ GRAAA 161_ VLLGC 166_ APAAA 171_ AAATT 176_ TSEAT 181_ PREER 186_ APAWA 191_ AEPRL 196_ HAASG 201_ AAAAR 206_ LLKPE 211_ LQVCV 216_ FCRNN 221_ KEAMA 226_ LYTTH 231_ ILKGP 236_ DGRVL 241_ CPVLR 246_ RYTCP 251_ LCGAS 256_ GDNAH 261_ TIKYC 266_ PLSKV 271_ PPPPA 276_ RPPPR 281_ SARDG 286_PPGKK
1: May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that associates with the 3'-UTR of mRNA targets. Capable of interfering with the proadhesive and anti-invasive functions of E-cadherin. Up-regulates the production of MMP14 to promote tumor cell invasion