C-type lectin domain family 2 member B (Activation-induced C-type lectin) (C-type lectin superfamily member 2) (IFN-alpha-2b-inducing-related protein 1)
1_MMTKH 6_ KKCFI 11_ IVGVL 16_ ITTNI 21_ ITLIV 26_ KLTRD 31_ SQSLC 36_ PYDWI 41_ GFQNK 46_ CYYFS 51_ KEEGD 56_ WNSSK 61_ YNCST 66_ QHADL 71_ TIIDN 76_ IEEMN 81_ FLRRY 86_ KCSSD 91_ HWIGL 96_ KMAKN 101_ RTGQW 106_ VDGAT 111_ FTKSF 116_ GMRGS 121_ EGCAY 126_ LSDDG 131_ AATAR 136_ CYTER 141_KWICR
1: Membrane-bound protein expressed on myeloid cells which acts as a ligand to stimulate the activating receptor NKp80/KLRF1, expressed on the surface of natural killer (NK) cells. In turn, stimulates NK-cell cytotoxicity and cytokine production leading to the cytolysis of malignant CLEC2B-expressing myeloid cells