GPI mannosyltransferase 3 (EC 2.4.1.-) (GPI mannosyltransferase III) (GPI-MT-III) (Phosphatidylinositol-glycan biosynthesis class B protein) (PIG-B)
1_MRRPL 6_ SKCGM 11_ EPGGG 16_ DASLT 21_ LHGLQ 26_ NRSHG 31_ KIKLR 36_ KRKST 41_ LYFNT 46_ QEKSA 51_ RRRGD 56_ LLGEN 61_ IYLLL 66_ FTIAL 71_ RILNC 76_ FLVQT 81_ SFVPD 86_ EYWQS 91_ LEVSH 96_ HMVFN 101_ YGYLT 106_ WEWTE 111_ RLRSY 116_ TYPLI 121_ FASIY 126_ KILHL 131_ LGKDS 136_ VQLLI 141_ WIPRL 146_ AQALL 151_ SAVAD 156_ VRLYS 161_ LMKQL 166_ ENQEV 171_ ARWVF 176_ FCQLC 181_ SWFTW 186_ YCCTR 191_ TLTNT 196_ METVL 201_ TIIAL 206_ FYYPL 211_ EGSKS 216_ MNSVK 221_ YSSLV 226_ ALAFI 231_ IRPTA 236_ VILWT 241_ PLLFR 246_ HFCQE 251_ PRKLD 256_ LILHH 261_ FLPVG 266_ FVTLS 271_ LSLMI 276_ DRIFF 281_ GQWTL 286_ VQFNF 291_ LKFNV 296_ LQNWG 301_ TFYGS 306_ HPWHW 311_ YFSQG 316_ FPVIL 321_ GTHLP 326_ FFIHG 331_ CYLAP 336_ KRYRI 341_ LLVTV 346_ LWTLL 351_ VYSML 356_ SHKEF 361_ RFIYP 366_ VLPFC 371_ MVFCG 376_ YSLTH 381_ LKTWK 386_ KPALS 391_ FLFLS 396_ NLFLA 401_ LYTGL 406_ VHQRG 411_ TLDVM 416_ SHIQK 421_ VCYNN 426_ PNKSS 431_ ASIFI 436_ MMPCH 441_ STPYY 446_ SHVHC 451_ PLPMR 456_ FLQCP 461_ PDLTG 466_ KSHYL 471_ DEADV 476_ FYLNP 481_ LNWLH 486_ REFHD 491_ DASLP 496_ THLIT 501_ FSILE 506_ EEISA 511_ FLISS 516_ NYKRT 521_ AVFFH 526_ THLPE 531_ GRIGS 536_ HIYVY 541_ ERKLK 546_GKFNM
1: Alpha-1,2-mannosyltransferase that catalyzes the transfer of the third mannose, via an alpha-1,2 bond, from a dolichol-phosphate-mannose (Dol-P-Man) to an alpha-D-Man-(1->6)-2-PEtn-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol intermediate to generate an alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-2-PEtn-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol (also termed H6) and participates in the nineth step of the glycosylphosphatidylinositol-anchor biosynthesis (PubMed:8861954). May also add the third mannose to an alpha-D-Man-(1->6)-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol (also termed H3) intermediate generating an alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol (also termed H4) (Probable)