DCN1-like protein 4 (DCNL4) (DCUN1 domain-containing protein 4) (Defective in cullin neddylation protein 1-like protein 4)
1_MHSDA 6_ AAVNF 11_ QLNSH 16_ LSTLA 21_ NIHKI 26_ YHTLN 31_ KLNLT 36_ EDIGQ 41_ DDHQT 46_ GSLRS 51_ CSSSD 56_ CFNKV 61_ MPPRK 66_ KRRPA 71_ SGDDL 76_ SAKKS 81_ RHDSM 86_ YRKYD 91_ STRIK 96_ TEEEA 101_ FSSKR 106_ CLEWF 111_ YEYAG 116_ TDDVV 121_ GPEGM 126_ EKFCE 131_ DIGVE 136_ PENVV 141_ MLVLA 146_ WKLDA 151_ QNMGY 156_ FTLQE 161_ WLKGM 166_ TSLQC 171_ DTTEK 176_ LRNTL 181_ DYLRS 186_ FLNDS 191_ TNFKL 196_ IYRYA 201_ FDFAR 206_ EKDQR 211_ SLDIN 216_ TAKCM 221_ LGLLL 226_ GKIWP 231_ LFPVF 236_ HQFLE 241_ QSKYK 246_ VINKD 251_ QWCNV 256_ LEFSR 261_ TINLD 266_ LSNYD 271_ EDGAW 276_ PVLLD 281_ EFVEW 286_YKDKQ
1: Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which are necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs)