Rap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF) (Related to Epac) (Repac)
1_MGSSR 6_ LRVFD 11_ PHLER 16_ KDSAA 21_ ALSDR 26_ ELPLP 31_ TFDVP 36_ YFKYI 41_ DEEDE 46_ DDEWS 51_ SRSQS 56_ STEDD 61_ SVDSL 66_ LSDRY 71_ VVVSG 76_ TPEKI 81_ LEHLL 86_ NDLHL 91_ EEVQD 96_ KETET 101_ LLDDF 106_ LLTYT 111_ VFMTT 116_ DDLCQ 121_ ALLRH 126_ YSAKK 131_ YQGKE 136_ ENSDV 141_ PRRKR 146_ KVLHL 151_ VSQWI 156_ ALYKD 161_ WLPED 166_ EHSKM 171_ FLKTI 176_ YRNVL 181_ DDVYE 186_ YPILE 191_ KELKE 196_ FQKIL 201_ GMHRR 206_ HTVDE 211_ YSPQK 216_ KNKAL 221_ FHQFS 226_ LKENW 231_ LQHRG 236_ TVTET 241_ EEIFC 246_ HVYIT 251_ EHSYV 256_ SVKAK 261_ VSSIA 266_ QEILK 271_ VVAEK 276_ IQYAE 281_ EDLAL 286_ VAITF 291_ SGEKH 296_ ELQPN 301_ DLVIS 306_ KSLEA 311_ SGRIY 316_ VYRKD 321_ LADTL 326_ NPFAE 331_ NEESQ 336_ QRSMR 341_ ILGMN 346_ TWDLA 351_ LELMN 356_ FDWSL 361_ FNSIH 366_ EQELI 371_ YFTFS 376_ RQGSG 381_ EHTAN 386_ LSLLL 391_ QRCNE 396_ VQLWV 401_ ATEIL 406_ LCSQL 411_ GKRVQ 416_ LVKKF 421_ IKIAA 426_ HCKAQ 431_ RNLNS 436_ FFAIV 441_ MGLNT 446_ ASVSR 451_ LSQTW 456_ EKIPG 461_ KFKKL 466_ FSELE 471_ SLTDP 476_ SLNHK 481_ AYRDA 486_ FKKMK 491_ PPKIP 496_ FMPLL 501_ LKDVT 506_ FIHEG 511_ NKTFL 516_ DNLVN 521_ FEKLH 526_ MIADT 531_ VRTLR 536_ HCRTN 541_ QFGDL 546_ SPKEH 551_ QELKS 556_ YVNHL 561_ YVIDS 566_ QQALF 571_ELSHR
1: Guanine nucleotide exchange factor (GEF) for RAP1A, RAP2A and MRAS/M-Ras-GTP. Its association with MRAS inhibits Rap1 activation