Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK)
1_MYNTV 6_ WSMDR 11_ DDADW 16_ REVMM 21_ PYSTE 26_ LIFYI 31_ EMDPP 36_ ALPPK 41_ PPKPM 46_ TSAVP 51_ NGMKD 56_ SSVSL 61_ QDAEW 66_ YWGDI 71_ SREEV 76_ NDKLR 81_ DMPDG 86_ TFLVR 91_ DASTK 96_ MQGDY 101_ TLTLR 106_ KGGNN 111_ KLIKI 116_ YHRDG 121_ KYGFS 126_ DPLTF 131_ NSVVE 136_ LINHY 141_ HHESL 146_ AQYNP 151_ KLDVK 156_ LMYPV 161_ SRYQQ 166_ DQLVK 171_ EDNID 176_ AVGKK 181_ LQEYH 186_ SQYQE 191_ KSKEY 196_ DRLYE 201_ EYTRT 206_ SQEIQ 211_ MKRTA 216_ IEAFN 221_ ETIKI 226_ FEEQC 231_ HTQEQ 236_ HSKEY 241_ IERFR 246_ REGNE 251_ KEIER 256_ IMMNY 261_ DKLKS 266_ RLGEI 271_ HDSKM 276_ RLEQD 281_ LKNQA 286_ LDNRE 291_ IDKKM 296_ NSIKP 301_ DLIQL 306_ RKIRD 311_ QHLVW 316_ LNHKG 321_ VRQKR 326_ LNVWL 331_ GIKNE 336_ DADEN 341_ YFINE 346_ EDENL 351_ PHYDE 356_ KTWFV 361_ EDINR 366_ VQAED 371_ LLYGK 376_ PDGAF 381_ LIRES 386_ SKKGC 391_ YACSV 396_ VADGE 401_ VKHCV 406_ IYSTA 411_ RGYGF 416_ AEPYN 421_ LYSSL 426_ KELVL 431_ HYQQT 436_ SLVQH 441_ NDSLN 446_ VRLAY 451_ PVHAQ 456_MPSLC
1: Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1