AP-3 complex subunit sigma-1 (AP-3 complex subunit sigma-3A) (Adaptor-related protein complex 3 subunit sigma-1) (Clathrin-associated/assembly/adaptor protein, small 3) (Sigma-3A-adaptin) (Sigma3A-adaptin) (Sigma-adaptin 3a)
1_MIKAI 6_ LIFNN 11_ HGKPR 16_ LSKFY 21_ QPYSE 26_ DTQQQ 31_ IIRET 36_ FHLVS 41_ KRDEN 46_ VCNFL 51_ EGGLL 56_ IGGSD 61_ NKLIY 66_ RHYAT 71_ LYFVF 76_ CVDSS 81_ ESELG 86_ ILDLI 91_ QVFVE 96_ TLDKC 101_ FENVC 106_ ELDLI 111_ FHVDK 116_ VHNIL 121_ AEMVM 126_ GGMVL 131_ ETNMN 136_ EIVTQ 141_ IDAQN 146_ KLEKS 151_ EAGLA 156_ GAPAR 161_ AVSAV 166_ KNMNL 171_ PEIPR 176_ NINIG 181_ DISIK 186_VPNLP
1: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals