Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain) (Surfactant protein receptor SP-R210) (SP-R210)
1_MFNLM 6_ KKDKD 11_ KDGGR 16_ KEKKE 21_ KKEKK 26_ ERMSA 31_ AELRS 36_ LEEMS 41_ LRRGF 46_ FNLNR 51_ SSKRE 56_ SKTRL 61_ EISNP 66_ IPIKV 71_ ASGSD 76_ LHLTD 81_ IDSDS 86_ NRGSV 91_ ILDSG 96_ HLSTA 101_ SSSDD 106_ LKGEE 111_ GSFRG 116_ SVLQR 121_ AAKFG 126_ SLAKQ 131_ NSQMI 136_ VKRFS 141_ FSQRS 146_ RDESA 151_ SETST 156_ PSEHS 161_ AAPSP 166_ QVEVR 171_ TLEGQ 176_ LVQHP 181_ GPGIP 186_ RPGHR 191_ SRAPE 196_ LVTKK 201_ FPVDL 206_ RLPPV 211_ VPLPP 216_ PTLRE 221_ LELQR 226_ RPTGD 231_ FGFSL 236_ RRTTM 241_ LDRGP 246_ EGQAC 251_ RRVVH 256_ FAEPG 261_ AGTKD 266_ LALGL 271_ VPGDR 276_ LVEIN 281_ GHNVE 286_ SKSRD 291_ EIVEM 296_ IRQSG 301_ DSVRL 306_ KVQPI 311_ PELSE 316_ LSRSW 321_ LRSGE 326_ GPRRE 331_ PSDAK 336_ TEEQI 341_ AAEEA 346_ WNETE 351_ KVWLV 356_ HRDGF 361_ SLASQ 366_ LKSEE 371_ LNLPE 376_ GKVRV 381_ KLDHD 386_ GAILD 391_ VDEDD 396_ VEKAN 401_ APSCD 406_ RLEDL 411_ ASLVY 416_ LNESS 421_ VLHTL 426_ RQRYG 431_ ASLLH 436_ TYAGP 441_ SLLVL 446_ GPRGA 451_ PAVYS 456_ EKVMH 461_ MFKGC 466_ RREDM 471_ APHIY 476_ AVAQT 481_ AYRAM 486_ LMSRQ 491_ DQSII 496_ LLGSS 501_ GSGKT 506_ TSCQH 511_ LVQYL 516_ ATIAG 521_ ISGNK 526_ VFSVE 531_ KWQAL 536_ YTLLE 541_ AFGNS 546_ PTIIN 551_ GNATR 556_ FSQIL 561_ SLDFD 566_ QAGQV 571_ ASASI 576_ QTMLL 581_ EKLRV 586_ ARRPA 591_ SEATF 596_ NVFYY 601_ LLACG 606_ DGTLR 611_ TELHL 616_ NHLAE 621_ NNVFG 626_ IVPLA 631_ KPEEK 636_ QKAAQ 641_ QFSKL 646_ QAAMK 651_ VLGIS 656_ PDEQK 661_ ACWFI 666_ LAAIY 671_ HLGAA 676_ GATKE 681_ AAEAG 686_ RKQFA 691_ RHEWA 696_ QKAAY 701_ LLGCS 706_ LEELS 711_ SAIFK 716_ HQHKG 721_ GTLQR 726_ STSFR 731_ QGPEE 736_ SGLGD 741_ GTGPK 746_ LSALE 751_ CLEGM 756_ AAGLY 761_ SELFT 766_ LLVSL 771_ VNRAL 776_ KSSQH 781_ SLCSM 786_ MIVDT 791_ PGFQN 796_ PEQGG 801_ SARGA 806_ SFEEL 811_ CHNYT 816_ QDRLQ 821_ RLFHE 826_ RTFVQ 831_ ELERY 836_ KEENI 841_ ELAFD 846_ DLEPP 851_ TDDSV 856_ AAVDQ 861_ ASHQS 866_ LVRSL 871_ ARTDE 876_ ARGLL 881_ WLLEE 886_ EALVP 891_ GASED 896_ TLLER 901_ LFSYY 906_ GPQEG 911_ DKKGQ 916_ SPLLH 921_ SSKPH 926_ HFLLG 931_ HSHGT 936_ NWVEY 941_ NVTGW 946_ LNYTK 951_ QNPAT 956_ QNAPR 961_ LLQDS 966_ QKKII 971_ SNLFL 976_ GRAGS 981_ ATVLS 986_ GSIAG 991_ LEGGS 996_ QLALR 1001_ RATSM 1006_ RKTFT 1011_ TGMAA 1016_ VKKKS 1021_ LCIQM 1026_ KLQVD 1031_ ALIDT 1036_ IKKSK 1041_ LHFVH 1046_ CFLPV 1051_ AEGWA 1056_ GEPRS 1061_ ASSRR 1066_ VSSSS 1071_ ELDLP 1076_ SGDHC 1081_ EAGLL 1086_ QLDVP 1091_ LLRTQ 1096_ LRGSR 1101_ LLDAM 1106_ RMYRQ 1111_ GYPDH 1116_ MVFSE 1121_ FRRRF 1126_ DVLAP 1131_ HLTKK 1136_ HGRNY 1141_ IVVDE 1146_ RRAVE 1151_ ELLEC 1156_ LDLEK 1161_ SSCCM 1166_ GLSRV 1171_ FFRAG 1176_ TLARL 1181_ EEQRD 1186_ EQTSR 1191_ NLTLF 1196_ QAACR 1201_ GYLAR 1206_ QHFKK 1211_ RKIQD 1216_ LAIRC 1221_ VQKNI 1226_ KKNKG 1231_ VKDWP 1236_ WWKLF 1241_ TTVRP 1246_ LIEVQ 1251_ LSEEQ 1256_ IRNKD 1261_ EEIQQ 1266_ LRSKL 1271_ EKAEK 1276_ ERNEL 1281_ RLNSD 1286_ RLESR 1291_ ISELT 1296_ SELTD 1301_ ERNTG 1306_ ESASQ 1311_ LLDAE 1316_ TAERL 1321_ RAEKE 1326_ MKELQ 1331_ TQYDA 1336_ LKKQM 1341_ EVMEM 1346_ EVMEA 1351_ RLIRA 1356_ AEING 1361_ EVDDD 1366_ DAGGE 1371_ WRLKY 1376_ ERAVR 1381_ EVDFT 1386_ KKRLQ 1391_ QEFED 1396_ KLEVE 1401_ QQNKR 1406_ QLERR 1411_ LGDLQ 1416_ ADSEE 1421_ SQRAL 1426_ QQLKK 1431_ KCQRL 1436_ TAELQ 1441_ DTKLH 1446_ LEGQQ 1451_ VRNHE 1456_ LEKKQ 1461_ RRFDS 1466_ ELSQA 1471_ HEEAQ 1476_ REKLQ 1481_ REKLQ 1486_ REKDM 1491_ LLAEA 1496_ FSLKQ 1501_ QLEEK 1506_ DMDIA 1511_ GFTQK 1516_ VVSLE 1521_ AELQD 1526_ ISSQE 1531_ SKDEA 1536_ SLAKV 1541_ KKQLR 1546_ DLEAK 1551_ VKDQE 1556_ EELDE 1561_ QAGTI 1566_ QMLEQ 1571_ AKLRL 1576_ EMEME 1581_ RMRQT 1586_ HSKEM 1591_ ESRDE 1596_ EVEEA 1601_ RQSCQ 1606_ KKLKQ 1611_ MEVQL 1616_ EEEYE 1621_ DKQKV 1626_ LREKR 1631_ ELEGK 1636_ LATLS 1641_ DQVNR 1646_ RDFES 1651_ EKRLR 1656_ KDLKR 1661_ TKALL 1666_ ADAQL 1671_ MLDHL 1676_ KNSAP 1681_ SKREI 1686_ AQLKN 1691_ QLEES 1696_ EFTCA 1701_ AAVKA 1706_ RKAME 1711_ VEIED 1716_ LHLQI 1721_ DDIAK 1726_ AKTAL 1731_ EEQLS 1736_ RLQRE 1741_ KNEIQ 1746_ NRLEE 1751_ DQEDM 1756_ NELMK 1761_ KHKAA 1766_ VAQAS 1771_ RDLAQ 1776_ INDLQ 1781_ AQLEE 1786_ ANKEK 1791_ QELQE 1796_ KLQAL 1801_ QSQVE 1806_ FLEQS 1811_ MVDKS 1816_ LVSRQ 1821_ EAKIR 1826_ ELETR 1831_ LEFER 1836_ TQVKR 1841_ LESLA 1846_ SRLKE 1851_ NMEKL 1856_ TEERD 1861_ QRIAA 1866_ ENREK 1871_ EQNKR 1876_ LQRQL 1881_ RDTKE 1886_ EMGEL 1891_ ARKEA 1896_ EASRK 1901_ KHELE 1906_ MDLES 1911_ LEAAN 1916_ QSLQA 1921_ DLKLA 1926_ FKRIG 1931_ DLQAA 1936_ IEDEM 1941_ ESDEN 1946_ EDLIN 1951_ SLQDM 1956_ VTKYQ 1961_ KRKNK 1966_ LEGDS 1971_ DVDSE 1976_ LEDRV 1981_ DGVKS 1986_ WLSKN 1991_ KGPSK 1996_ AASDD 2001_ GSLKS 2006_ SSPTS 2011_ YWKSL 2016_ APDRS 2021_ DDEHD 2026_ PLDNT 2031_ SRPRY 2036_ SHSYL 2041_ SDSDT 2046_EAKLT
1: May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus (PubMed:19837035, PubMed:23345592). Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By similarity). Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking (PubMed:25965346). Acts as a receptor of surfactant-associated protein A (SFTPA1/SP-A) and plays an important role in internalization and clearance of SFTPA1-opsonized S.aureus by alveolar macrophages (PubMed:16087679, PubMed:21123169). Strongly enhances natural killer cell cytotoxicity (PubMed:27467939)