USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN-tre)
1_MNSDQ 6_ DVALK 11_ LAQER 16_ AEIVA 21_ KYDRG 26_ REGAE 31_ IEPWE 36_ DADYL 41_ VYKVT 46_ DRFGF 51_ LHEEE 56_ LPDHN 61_ VAVER 66_ QKHLE 71_ IERTT 76_ KWLKM 81_ LKGWE 86_ KYKNT 91_ EKFHR 96_ RIYKG 101_ IPLQL 106_ RGEVW 111_ ALLLE 116_ IPKMK 121_ EETRD 126_ LYSKL 131_ KHRAR 136_ GCSPD 141_ IRQID 146_ LDVNR 151_ TFRDH 156_ IMFRD 161_ RYGVK 166_ QQSLF 171_ HVLAA 176_ YSIYN 181_ TEVGY 186_ CQGMS 191_ QITAL 196_ LLMYM 201_ NEEDA 206_ FWALV 211_ KLFSG 216_ PKHAM 221_ HGFFV 226_ QGFPK 231_ LLRFQ 236_ EHHEK 241_ ILNKF 246_ LSKLK 251_ QHLDS 256_ QEIYT 261_ SFYTM 266_ KWFFQ 271_ CFLDR 276_ TPFTL 281_ NLRIW 286_ DIYIF 291_ EGERV 296_ LTAMS 301_ YTILK 306_ LHKKH 311_ LMKLS 316_ MEELV 321_ EFFQE 326_ TLAKD 331_ FFFED 336_ DFVIE 341_ QLQIS 346_ MTELK 351_ RAKLD 356_ LPEPG 361_ KEDEY 366_ PKKPL 371_ GQLPP 376_ ELQSW 381_ GVHHL 386_ SNGQR 391_ SVGRP 396_ SPLAS 401_ GRRES 406_ GAPHR 411_ RHEHS 416_ PHPQS 421_ RTGTP 426_ ERAQP 431_ PRRKS 436_ VEEES 441_ KKLKD 446_ EADFQ 451_ RKLPS 456_ GPQDS 461_ SRQYN 466_ HAAAN 471_ QNSNA 476_ TSNIR 481_ KEFVP 486_ KWNKP 491_ SDVSA 496_ TERTA 501_ KYTME 506_ GKGRA 511_ AHPAL 516_ AVTVP 521_ GPAEV 526_ RVSNV 531_ RPKMK 536_ ALDAE 541_ DGKRG 546_ STASQ 551_ YDNVP 556_ GPELD 561_ SGASV 566_ EEALE 571_ RAYSQ 576_ SPRHA 581_ LYPPS 586_ PRKHA 591_ EPSSS 596_ PSKVS 601_ NKFTF 606_ KVQPP 611_ SHARY 616_ PSQLD 621_ GEARG 626_ LAHPP 631_ SYSNP 636_ PVYHG 641_ NSPKH 646_ FPTAN 651_ SSFAS 656_ PQFSP 661_ GTQLN 666_ PSRRP 671_ HGSTL 676_ SVSAS 681_ PEKSY 686_ SRPSP 691_ LVLPS 696_ SRIEV 701_ LPVDT 706_ GAGGY 711_ SGNSG 716_ SPKNG 721_ KLIIP 726_ PVDYL 731_ PDNRT 736_ WSEVS 741_ YTYRP 746_ ETQGQ 751_ SWTRD 756_ ASRGN 761_ LPKYS 766_ AFQLA 771_ PFQDH 776_ GLPAV 781_ SVDSP 786_ VRYKA 791_ SPAAE 796_ DASPS 801_ GYPYS 806_ GPPPP 811_ AYHYR 816_ NRDGL 821_SIQES
1: Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex